带科绦虫主要宿主保护性抗原及其分子生物学特性  

Major Host-protective Antigens of Taeniidae cestode and Their Molecular Biological Characteristics

作　　者：岳龙[1] 付宝权[1] 

机构地区：[1]中国农业科学院兰州兽医研究所,兰州730046

出　　处：《中国寄生虫学与寄生虫病杂志》2014年第6期469-473,共5页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：带科绦虫是棘球蚴病、囊尾蚴病和绦虫病的病原体,可感染牛、羊等家畜,造成巨大的经济损失,也可感染人导致发病甚至死亡。近年来,研究者在绦虫中发现了许多具有宿主保护作用的抗原分子,以这些抗原制备的基因重组蛋白疫苗已用于防治羊绦虫、牛带绦虫、猪带绦虫、多房棘球绦虫和细粒棘球绦虫等引起的寄生虫病。本文就带科绦虫的主要宿主保护性抗原及其分子生物学特性作一综述。Taeniidae cestodes are the pathogens of cysticercosis and hydatid disease， these diseases lead to substantial economic losses in animal husbandry and cause morbidity and mortality in human population. In recent years， many host-protective antigens of Taeniidae cestodes has been found， and their recombinant protein vaccines have been developed against several species， such as Taenia ovis， T. saginata， T. solium， Echinococcus granulosus， and E. multilocularis. This paper focuses on the major host-protective antigens of Taeniidae cestodes and their molecular biological characteristics.

关 键 词：带科绦虫 宿主保护性抗原 分子生物学 

分 类 号：R383.3[医药卫生—医学寄生虫学]