小学生非酒精性脂肪肝相关因素分析  

The analysis of risk factors of nonalcoholic fatty liver diseases in primary school students

作　　者：徐仁应[1] 冯海霞[1] 万燕萍[1] 周一泉[1] 陆丽萍[1] 张晓敏[1] 陈之琦[1] 蒋莹[1] 谈韬[1] 吴颖洁[1] 

机构地区：[1]上海交通大学医学院附属仁济医院临床营养科,上海200127

出　　处：《临床儿科杂志》2014年第12期1141-1144,共4页Journal of Clinical Pediatrics

基　　金：世界健康基金会基金资助项目(No.AFINS-HOPE-2013-06)

摘　　要：目的：探讨小学生非酒精性脂肪肝（NAFLD）发生的相关因素。方法对上海市浦东新区5所小学2163名（男1120名、女1043名）学生进行横断面调查。测量身高、体质量、腰围、体脂肪含量，问卷调查法采集出生体质量、是否母乳喂养及父母身高、体质量。以肝脏超声诊断NAFLD，分析NAFLD的相关因素。结果 NAFLD发生率为8.9%，男生发生率明显高于女生，差异有统计学意义（12.5%对5.0%，P＜0.01）。多元Logistic回归显示，性别为男性（OR=1.97，95%CI：1.21～3.21）、体脂含量高（OR=1.12，95%CI：1.07～1.17）是NAFLD发生的独立危险因素；而体质指数正常（OR=0.09，95%CI：0.04～0.19）是NAFLD发生的独立保护因素。结论小学男生NAFLD发生率明显高于女生；对于超重、体脂肪含量高的学生，应警惕NAFLD的发生。Objective To evaluate the relationship between birth weight and nonalcoholic fatty liver diseases （NAFLD） in Chinese primary school students. Methods A cross-section study was conducted in ifve elementary schools in Gao Hang Town, Shanghai and 2163 students were enrolled in the study （1120 boys/1043 girls）. Height, body weight, waist circumference and per-cent of body fat （bioelectrical impedance analysis） were measured by professional nutritionist after training. Birth weight, feeding pattern, height and body weight of parents were obtained by a self-completed questionnaire. NAFLD was diagnosed by ultra-sound. The risk factors of NAFLD were analyzed. Results The prevalence of NAFLD in the study population was 8.9%. The prevalence of NAFLD was signiifcantly higher in boys than that in girls （12.5%vs 5.0%, P〈0.01）. Logistic regression showed that sex （OR=1.97, 95%CI：1.21-3.21） and percent of body fat （OR=1.12, 95%CI：1.07-1.17） were the risk factors of NAFLD, and normal BMI was the protective factor of NAFLD （OR=0.09, 95%CI：0.04-0.19） in the study population. Conclusions The pre-valence of NAFLD is higher in boys than that in girls. Also overweight, and high percent of body fat are risk factors of NAFLD in children.

关 键 词：体质指数 腰围 体脂肪含量 出生体质量 非酒精性脂肪肝 

分 类 号：R725.7[医药卫生—儿科]