超声内镜在消化道间叶源性肿瘤诊断的价值  

Diagnostic Value of Endoscopic Ultrasonography in the Diagnosis of Gastrointestinal Mesenchymal Tumors

作　　者：陈明锴[1] 刘云燕[1] 丁百静[2] 李生[2] 戴敏[3] 

机构地区：[1]武汉大学人民医院消化内科,430060 [2]安徽省芜湖市第二人民医院消化内科,241000 [3]安徽省芜湖市第二人民医院病理科,241000

出　　处：《医学研究杂志》2014年第12期118-121,共4页Journal of Medical Research

摘　　要：目的 探讨超声内镜（endoscopic ultrasonography,EUS）在消化道间叶源性肿瘤（gastrointestinal mesenchyInal tumors,GIMTs）中的诊断价值.方法 回顾性分析笔者医院2012年5月～2013年11月经EUS发现102例GIMTs的临床相关资料,通过与病理结果比较分析EUS在GIMTs中诊断的价值.结果 EUS初步诊断间质瘤44例、平滑肌瘤47例、脂肪瘤11例,其中85例经病理和（或）免疫组织化学检查,76例符合超声内镜诊断,符合率为89.4％.超声内镜对脂肪瘤诊断的敏感度、特异性、阳性预测值、阴性预测值均为100.0％;对间质瘤和平滑肌瘤诊断的敏感度、特异性、阳性预测值、阴性预测值分别为100.0％ vs 74.5％,77.8％ vs 91.1％,67.4％ vs 71.4％,100.0％ vs 95.3％.结论 应用超声内镜检查对于判断消化道间叶源性肿瘤具有重要的诊断价值,但对一些少见、不典型疾病的诊断还有待于进一步提高.Objective To evaluate the value of endoscopic ultrasonography （EUS） in the diagnosis of gastrointestinal mesenchymal tumors （GIMTs） and to figure out reasons of misdiagnosis.Methods A total of 102 cases of GIMTs were detected and collected in endoscopy center from May 2012 to November 2013,of which EUS findings and pathological characteristics were studied retrospectively.Results 44 cases of stromal tumor,47 cases of leiomyoma and 11 cases of lipomas were found in EUS.Of these,85 cases that underwent pathological examinations and immunohistochemical examinations,76 cases were diagnosed correctly and 9 cases were misdiagnosed by EUS.The sensitivity,specificity,positive predictive value and negative predictive value of EUS in the diagnosis of lipoma were 100.0％ ;the sensitivity,specificity,positive predictive value,and negative predictive value of EUS on the diagnosis of stromal tumors and leiomyomawere 100.0 ％ vs74.5％,77.8％ vs91.1％,67.4％ vs71.4％,100.0％ vs95.3％,respectively.Conclusion EUS plays a critical role in the diagnosis of gastrointestinal mesenchymal tumors,however,the value of EUS still needs to be further improved for some rare or atypical cases.

关 键 词：超声内镜 消化道间叶源性肿瘤 诊断价值 

分 类 号：R4[医药卫生—临床医学]