我院912例药品不良反应报告统计分析  

Statistical analysis of 912 adverse drug reaction reports in our hospital

作　　者：彭评志[1] 蒙光义[1] 林海佳[2] 庞家莲[1] 莫金权[3] 严浩林[3] 刘明[3] 

机构地区：[1]广西玉林市第一人民医院药学部,玉林537000 [2]广西医科大学药学院,南宁530021 [3]广西玉林市第一人民医院医务部,玉林537000

出　　处：《西北药学杂志》2015年第1期90-93,共4页Northwest Pharmaceutical Journal

摘　　要：目的探讨我院药品不良反应（ADR）发生的规律和特点,以促进临床合理用药。方法采用回顾性分析方法,对我院2012~2013年912例药品不良反应报告进行分类统计与分析。结果 912例ADR中,年龄大于60岁患者占31.91%,以抗菌药物诱发的ADR居多（32.02%）,静脉滴注给药是引发ADR的主要途径（74.12%）,最常见临床表现为皮肤及其附件损害（36.18%）,绝大部分ADR经过相关处理后能够完全治愈（55.92%）或者好转（42.76%）。结论医务人员应加强药品ADR监测,密切观察患者用药后的临床表现和反应,合理指导用药,减少ADR的发生。Objective To investigate the characteristics and regularity of adverse drug reaction （ADR） in our hospital for promoting rational drug use. Methods By retrospective study, 912 ADR reports in our hospital during 2012 2013 were analyzed statistical-ly. Results Among 912 ADR cases, 32. 02% ADR reports were caused by antibiotics drugs, patients aged over 60 occupied 31.91%, and intravenous route was the major cause of ADR（74.12%）. The lesion of skin and its appendants were the most com- mon clinical manifestation of ADR（36.18%）, such as erythra and pruritus. And most of them were improved（55.92%） or cured （42.76 %）. Conclusion Medical personnel should attach importance to supervise and report ADR, observe clinical manifestations and reaction, reduce the ADR,and promote rational drug use in the clinical work.

关 键 词：药物不良反应 安全用药 合理用药 统计分析 

分 类 号：R969.3[医药卫生—药理学]