冠心病猝死Tp-e间期延长的检测与临床意义  

Detection and clinical significance of Tp-e interval extension of sudden coronary death

作　　者：滕显娥[1] 李刘宁 王欢[1] 许超蕊[1] 杨兆颖[1] 

机构地区：[1]黑龙江省医院老年心内科,黑龙江哈尔滨150040

出　　处：《中国现代医生》2015年第3期26-28,共3页China Modern Doctor

基　　金：黑龙江省卫生厅课题(2012-358)

摘　　要：目的探讨冠心病猝死Tp-e间期延长的检测与临床意义。方法选取冠心病患者502例,其中冠心病猝死46例,设为猝死组,其余456例患者设为存活组。比较两组患者Tp-e、Tp-e/姨RR、按心率校正的QT间期(QTc)、左室射血分数(LVEF)的差异,并判断Tp-e间期延长对冠心病猝死的临床意义。结果与存活组比较,猝死组患者Tp-e、Tp-e/姨RR和QTc明显延长(P<0.05);与存活组比较,猝死组患者LVEF明显降低(P<0.05);Tp-e延长与冠心病猝死、QTc呈正相关(P<0.05)。结论冠心病猝死患者Tp-e间期明显延长,Tp-e间期延长可能成为冠心病猝死的危险预测指标。Objective To investigate the detection and clinical significance of Tp-e interval extension of sudden coro-nary death. Methods A total of 502 patients with coronary heart disease were selected, of which 46 patients with sud-den coronary death were assigned to the sudden death group and the other 456 patients were assigned to the survival group. The Tp-e, Tp-e/√RR , heart rate-corrected QT inverval （QTc） and left ventricular ejection fraction of the two groups were compared and the clinical significance of Tp-e interval extension for sudden coronary death was decided. Results Compared to the survival group, the sudden death group had significantly extended Tp-e, Tp-e/√RR and QTc（P〈0.05）;Compared to the survival group, the sudden death group had significantly reduced LVEF （P〈0.05）; Tp-e extension was positively correlated to sudden coronary death and QTc（P〈0.05）. Conclusion The Tp-e interval extended obviously in the patients with sudden coronary death and thus can serve as a predictive risk factor of sudden coronary death.

关 键 词：冠心病 猝死 TP-E间期 

分 类 号：R541.4[医药卫生—心血管疾病]