联合用药治疗小儿消化不良性腹泻的疗效及安全性  被引量:8

Effectiveness and safety analysis of the combination in treatment of pediatric digestive benign diarrhea

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作  者:肖荣玲[1] 李素芳[1] 楼晓芳[2] 

机构地区:[1]杭州市萧山区第一人民医院儿科,浙江杭州311200 [2]浙江大学医学院附属儿童医院儿科,浙江杭州310003

出  处:《中国现代医生》2015年第3期114-116,119,共4页China Modern Doctor

基  金:浙江省医药卫生平台骨干人才计划(2011RCA029)

摘  要:目的探讨对小儿消化不良性腹泻患儿采用思密达、酪酸梭菌活菌散联合醒脾养儿颗粒治疗的临床效果及安全性。方法收集112例消化不良性腹泻患儿作为研究对象,随机分为研究组与对照组,均为56例;对照组给予思密达治疗,研究组在对照组的基础上联合酪酸梭菌活菌散与醒脾养儿颗粒治疗。结果研究组的大便次数恢复正常时间、体温恢复正常时间、大便性状恢复正常时间均明显优于对照组,差异有统计学意义(P<0.05);研究组的总有效率为96.43%,明显优于对照组的73.21%,差异有统计学意义(P<0.05);治疗后研究组的HAMA评分显著低于对照组,差异有统计学意义(P<0.05);研究组的不良反应发生率为5.36%,与对照组相比差异无统计学意义(P>0.05)。结论对小儿消化不良性腹泻患儿采用思密达、酪酸梭菌活菌散联合醒脾养儿颗粒治疗,能有效、快速改善患儿的腹泻症状,疗效显著,值得推广。Objective To investigate the clinical effect and safety of Smecta, Clostridium butyricum powder particles combined with Xingpiyang&#39;er particles on pediatric digestive benign diarrhea. Methods All 112 cases of children with diarrhea indigestion as research subjects were randomly divided into study group and the control group, 56 cases in the control group were given smecta treatment, research group were given on the basis of the control group Clostridium and Xingpiyang’er particles. Results The study group stool frequency recovery time, body temperature returned to normal, stool recovery time was significantly better than the control group, the differences were statistically significant (P&lt;0.05);the total effective rate of research group was 96.43%,significantly better than 73.21% in the control group, the differ-ences were statistically significant (P&lt;0.05);after treatment, the HAMA score of research group was significantly lower than the control group, with statistical significance (P&lt;0.05);adverse reactions rate of research group was 5.36%, with no obvious difference compared to the control group (P&gt;0.05). Conclusion Children with indigestion diarrhea in chil-dren using smecta, Clostridium butyricum powder particle therapy combined Xingpiyang&#39;er particles particks, can ef-fectively and quickly improve the symptoms of children with diarrhea, the effect is significant, it is worth promoting.

关 键 词:消化不良 腹泻 醒脾养儿颗粒 

分 类 号:R725.7[医药卫生—儿科]

 

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