肝癌化疗栓塞前后肝储备功能检测临床分析  

The clinical analysis of the test of hepatic functional reserve before and after having chemoembolization for liver cancer

作　　者：高桂花[1] 张孝 锡林高娃[1] 

机构地区：[1]内蒙古医科大学第三附属医院感染疾病科,内蒙古包头014010 [2]包头市包钢三医院介入科

出　　处：《疾病监测与控制》2015年第1期28-29,共2页Journal of Diseases Monitor and Control

摘　　要：目的探讨肝癌化疗栓塞前后肝储备功能检测。方法回顾性分析57例原发性肝癌化疗栓塞术前、术后3天、1周、2周、4周的透明质酸酶(HA)、胆碱酯酶(CHE)、层黏蛋白(LN)、总胆红素(TBIL)、白蛋白(ALB)、凝血酶原时间(PT)指标检测、整理。结果术前Child A级、胆碱酯酶、透明质酸酶、层黏蛋白在正常至轻度异常范围,术后多数恢复良好无并发症;术前Child A级、B级、胆碱酯酶、透明质酸酶、层黏蛋白中度异常,术后恶化恢复差、发生严重并发症,有5例死于肝衰竭。结论在Child-Pugh分级基础上加测透明质酸酶、胆碱酯酶、层黏蛋白对评估肝储备功能有一定意义。Objective discuss the test of hepatic functional reserve before and after having chemoembolization for liver cancer. Methods Retrospectively analyze 57 cases of primary carcinoma of liver treated with chemoembolization. Test the arrange the data of HA, CHE, LN, TBIL, ALB and PT at the time of before the operation and 3 days, a week, two weeks,4weeks after the operation. Results Most of the patients with the level of child/k, CHE and LN at the range between normal and mildly abnormal before the operation recovered well and had no complication after the operation. Patients with moderately abnormal level of ChilA, B, CHE, HA and LN before operation recovered badly and even got worse and have serious complication, and 5 cases died from hepatic failure. Conclusion at the bases of child-pugh classification, add the test of HA, CHE, LN has a meaning of evaluating hepatic functional reserve.

关 键 词：肝储备功能 透明质酸酶 胆碱酯酶 

分 类 号：R735.7[医药卫生—肿瘤]