创伤导致急性肾损伤患者血浆脑钠肽值的变化及临床意义  

Explore the changes and clinical significance of plasma BNP values in patients with trauma induced acute kidney injury

作　　者：宋志[1] 赵秀[2] 滕玥[1] 崔岩[1] 侯明晓[1] 高燕[1] 

机构地区：[1]沈阳军区总医院急诊医学部全军重症(战)创伤救治中心,沈阳110016 [2]沈阳医学院口腔医学教研室

出　　处：《临床急诊杂志》2014年第12期716-718,共3页Journal of Clinical Emergency

基　　金：辽宁省科学技术计划项目(No:2013225089);中国博士后科学基金(No:2014M552693)

摘　　要：目的:探讨多发创伤导致急性肾损伤患者血浆脑钠肽水平的变化及临床意义。方法:对入住急诊监护室的85例创伤患者根据创伤的严重程度,按照ISS评分分为轻伤、重伤和危重伤3组,并监测入院时各组的血浆脑钠肽(BNP)值、血清肌酐(SCr)值、APACHEⅡ评分。将85例重症创伤患者分为死亡组及存活组,并监测血浆BNP值。结果:3组的血浆BNP值与血清肌酐值和APACHEⅡ评分呈正相关;死亡组患者的血浆BNP值明显高于存活组。结论:血浆脑钠肽水平的改变与创伤后急性肾损伤的严重程度相关,可作为判断伤情及预后的参考指标。Objective：To discuss the changes and clinical significance of plasma BNP values in patients with trauma induced acute kidney injury.Method：The 85 cases of trauma were divided into minor injury,serious injury and severe injury groups according to ISS score and were checked by the admission plasma BNP values,the value of SCr and APACHE Ⅱ score.Result：Three groups of plasma BNP values were positive correlated with SCr values and APACHE Ⅱscore.Plasma BNP levels of death group were higherly than the survival group.Conclusion：Plasma BNP values were associated with severity of trauma induced acute kidney injury,which might judging injuried sondition and evaluating prognosis.

关 键 词：创伤 脑钠肽 诊断 预后 

分 类 号：R641[医药卫生—外科学]