高尿酸血症与脂代谢紊乱的关系及其民族异质性分析  

Research of relationship between hyperuricemia and lipid metabolism disorders and its ethnic heterogeneity

作　　者：余家会[1] 张蓓[1] 古丽尼扎.哈力阿克帕尔 孙玉萍[1] 

机构地区：[1]新疆医科大学基础医学院病原学教研室,新疆乌鲁木齐830011 [2]新疆阿勒泰市医院检验科,新疆阿勒泰836500

出　　处：《国际检验医学杂志》2015年第2期145-147,共3页International Journal of Laboratory Medicine

基　　金：国家自然科学基金资助项目(81160115);国家重点基础研究发展计划(973计划)项目(2012CB722403)

摘　　要：目的探究维吾尔族（以下简称维族）及汉族两个民族人群高尿酸血症与脂代谢紊乱的关系及其民族异质性。方法 2013年1~10月采集8 197例维、汉族体检者的血液并进行UA以及脂代谢相关健康监测指标的检测,并采用SPSS17.0软件进行数据处理及统计学分析。结果维、汉族高尿酸血症、Ⅰ型高脂血症、Ⅱ型高脂血症以及低高密度脂蛋白血症的检出率差异均有统计学意义（P〈0.05）。高尿酸血症的维、汉族人群均易罹患Ⅰ型高脂血症。伴随着UA水平的升高,维、汉族三型高脂血症以及低高密度脂蛋白血症的检出率也逐渐升高（P〈0.05）。结论新疆维、汉族高尿酸血症与脂代谢紊乱存在民族差异性,高尿酸血症对这两个民族的脂代谢紊乱均产生促进作用。Objective To explore the relationship between hyperuricemia and lipid metabolism disorders and its ethnic heteroge- neity in Han,Uyghur nation. Methods A total of 8 197 blood samples were collected for detecting serum uric acid and some other relevant lipid metabolism indicators from January to October in 2013,and then analyzed by the software SPSS17.0. Results There were significant differences on the incidences of hyperuricemia, hyperlipidemia Ⅰ ,hyperlipidemia Ⅱ and low high-density lipopro- tein hyperlipidemia between Han nation and Uyghur nation（P（0.05）. The Han and Uyghur who had hyperuricemia were also easy to suffer from hyperlipidemia Ⅰ . As the uric acid level increased,the detection rate of hyperuricemia and lipid metabolism disorders were gradually increased in Han and Uygur nation （P〈0. 05）. Conclusion There are ethnic differences on the incidences of hype- ruricemia and lipid metabolism in Uyghur and Han nation,hyperuricemia influence on the lipid metabolism disorders.

关 键 词：血尿酸 高尿酸血症 脂代谢紊乱 

分 类 号：R589.7[医药卫生—内分泌]