人工麝香中五种重金属的含量测定  

Determination of the Contents of Five Heavy Metals in Artificial Musk

作　　者：刘薇[1] 邹秦文 程显隆[1] 李明华[1] 陈佳[1] 肖宣[3] 魏锋[1] 章菽 马双成[1] 

机构地区：[1]中国食品药品检定研究院中药民族药检定研究所,北京100050 [2]北京联馨药业有限公司技术部,北京102628 [3]中国医学科学院北京协和医学院药物研究所天然产物室,北京100050

出　　处：《中国医学科学院学报》2014年第6期610-613,共4页Acta Academiae Medicinae Sinicae

摘　　要：目的对人工麝香中5种有害重金属元素进行考察和测定,评估其安全性。方法采用电感耦合等离子体质谱法测定人工麝香中铅(Pb)、镉(Cd)、砷(As)、汞(Hg)、铜(Cu)含量。结果 10批人工麝香样品中Pb的含量小于0.35 mg/kg、Cd的含量小于0.05 mg/kg、As的含量小于0.30 mg/kg、Hg的含量小于0.20 mg/kg、Cu的含量小于4.50 mg/kg。结论人工麝香中5种重金属含量较低,符合药品质量安全的要求。Objective To evaluate the safety of artificial musk by determining its content of five hazard heavy metals. Method The contents of Pb, Cd, As, Hg, and Cu in artificial musk were detected using induc- tively coupled plasma-mass spectrometry. Result The contents of Pb, Cd, As, Hg, and Cu was less than 0. 35, 0. 05, 0. 30, 0. 20, and 4.50 mg/kg in artificial musk. Conclusion Artificial musk has low contents of heavy metals and therefore meets the safety and quality requirments.

关 键 词：电感耦合等离子体质谱 人工麝香 重金属 

分 类 号：R917[医药卫生—药物分析学]