多糖类止血材料的研究及应用进展  

Progress in the research and application of polysaccharide hemostatic materials

作　　者：姜毅[1] 王风华 段蕴铀[3] 

机构地区：[1]海军总医院呼吸内科,北京100048 [2]江苏昌吉永生物科技有限公司,江苏镇江212000 [3]海军总医院专家组,北京100048

出　　处：《解放军医学杂志》2014年第12期1004-1007,共4页Medical Journal of Chinese People's Liberation Army

摘　　要：局部止血是创伤处理的第一步,有效的止血手段可减少不必要的伤亡。止血材料需要具备良好的止血性能,优良的生物相容性,无毒副作用,无刺激性,易于加工成型等特点,而多糖具有多方面的优点,如来源丰富、结构简单、大多可被人体降解吸收、具有良好的生物相容性,多糖的结构基团还具有容易改性和复合的特点。本文分类总结了纤维素类、壳聚糖类、海藻酸盐、透明质酸、淀粉等各种多糖类止血材料的特性及其产品,为其临床应用和进一步研究提供依据。Local hemostasis is the first step in wound treatment, and effective hemostatic methods could reduce the number of unnecessary casualties. Hemostatic materials need to have good hemostatic properties, excellent biocompatibility, no toxic side effects, no irritation and easy to prepare. The polysaccharide has many advantages, including rich source, simple structures, absorbable and biodegradable, excellent biocompatibility. At present, it has been found that polysaccharide is easy to modify in structure and recombine. This paper summarizes the characteristics and products of polysaccharide hemostatic materials including celluloses, chitosans, alginate, hyaluronic acid, and starch in order to offer the indications for clinical application and further study.

关 键 词：多糖类 止血 纤维素 壳聚糖 海藻酸盐 透明质酸 

分 类 号：R605.972[医药卫生—急诊医学]