机构地区:[1]北京市结核病胸部肿瘤研究所首都医科大学附属北京胸科医院麻醉科,101149
出 处:《结核病与胸部肿瘤》2014年第4期259-262,共4页Tuberculosis and Thoracic Tumor
摘 要:目的探讨选择性肺隔离技术在右开胸非高段胸椎结核前路手术中的应用效果。方法2012年5月至2013年9月在北京胸科医院骨科因胸椎6以下结核择期行胸椎结核后路内固定+右开胸前路病灶清除术或右开胸前路内固定+病灶清除术的患者38例,按照随机数字表法分为2组:单侧肺通气组(OLV组)和选择性肺叶隔离组(SLB组)各19例。OLV组患者采用35号(女)或39号(男)左双腔气管导管,SLB组患者采用ID7.5(女)、ID8.0(男)加强单腔气管导管加支气管阻塞器行选择性右中下肺叶隔离。分别于左侧卧双肺通气10min(T1)、单侧肺通气或肺叶隔离30min(T2)、恢复双肺通气15min(T3)记录各时点的气道峰压(Ppeak)、平台压(Pplat),气道顺应性(Comp),收集动脉血做血气分析,术者评价术野暴露情况。采用SPSS11.0统计学软件进行分析,计量资料以“χ±s”表示,两组间比较采用独立样本t检验,组内各时点参数比较采用单因素方差分析,计数资料采用χ2检验。以P〈0.05为差异有统计学意义。结果T2时点,SLB组的PaO2高于OLV组[分别为(189.4±58.2)mmHg(1mmHg=0.133kPa)、(145.6±50.4)mmHg;t=4.28,P=0.00];SLB组的SaO2高于OLV组[分别为(99.6±0.3)%、(97.5±1.0)%;t=8.21,P=0.001]。T2时点,SLB组的Ppeak低于OLV组[分别为(18.1±3.2)cmH2O(1cmH2O=0.098kPa)、(20.5±4.1)cmH2O;t=2.15,P=0.04];SLB组的Pplat低于OLV组[分别为(16.3±3.2)cmH2O、(20.2±2.4)cmH2O;t=3.94,P=0.00],SLB组的Comp高于OLV组[分别为(34.8±14.5)ml/cmH2O、(26.4±15.2)ml/cmH2O;t=6.07,P=0.00]。术野暴露情况,OLV组18例优,1例良;SLB组17例优,2例良,差异无统计学意义(χ2=0.36,P=0.55)。结论选择性右中下肺叶隔离技术可明显改善右开胸非高段胸椎结核前路手术患者氧�Objective To evaluate selective lobar blockade in non-upper thoracic verte brae tuberculosis anterior approach operation via right thoracotomy. Methods Thirty-eight patients with non-upper thoracic vertebrae tuber culosis admitted in Beijing Chest Hospital from May, 2012 to September, 2013 undergoing anterior approach spinal operation via right thoracotomy were randomly divided to the doubl- lumen tube (OLV) group (n=19) and the selective lobar blockade(SLB) group(n=19). Anesthesia was induced and maintained routinely. The patients were intubated with F35 or F39 double-lumen tube in OLV group and were intubated with ID 7. 5 or ID 8.0 enforced singl-lumen tube and a endobronchial blocker into the bronchus intermedius in SLB group. The position of all endo bronchial tube was ensured with fiberoptic bronchoscope. Ppeak, Pplat, Comp and arterial blood gas analysis was performed and recorded at the following time point : 10 mins after two lung ventilation on left lateral decubitus position(T1), 30 mins after one lung ventilation or selective lobar blockade ventilation (T2), 15 mins after two lung ventilation resumed(T3). Results PaO2 and SaO2 of group SLB were higher than those of group OLV(P〈0.05) at 30 mins after one lung ventilation or selective lobar blockade ventilation (PaO2 : (189.4 ±58.2) mm Hg, (145.6 ± 50.4) mm Hg, t=4. 28, P=0. 00), SaO2 : 99. 6±0. 3%, 97. 5%± 1.0%, (t =8. 21, P=0. 00). Ppeak and Pplat of group SLB were lower than those of group OLV(P〈0. 05) at 30 mins after one lung ventilation or selective lobar blockade ventilation (Ppeak : (18. 1 ± 3.2) cm H2O, (20. 5 ± 4. 1) cm H2O, t=2. 15, P =0. 04) , Pplat : (16.3 ±3.2) cm H2O, (20. 2 ±2.4) cm H2O, (t=3.94, P=0. 00). Comp of group SLB were higher than those of group OLV at 30 mins after one lung ventilation or selective lobar blockade ventilation ((34. 8 ± 14. 5) ml/cmH2O, (26.4 ± 15.2) ml/cmH2O, t=6.07, P=0. 00). No statistical difference
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