2012-2013年韶关市流感病原学监测  

Etiology surveillance of influenza in Shaoguan city from 2012 to 2013

作　　者：邱灿林[1] 龚萍[1] 唐建红[1] 徐亮[1] 

机构地区：[1]韶关市疾病预防控制中心,广东韶关512028

出　　处：《热带医学杂志》2014年第12期1630-1632,共3页Journal of Tropical Medicine

摘　　要：目的对韶关市2012-2013年流感病原学监测结果进行分析,了解其病原学特点和流行病学特征,为今后流感防控提供科学依据。方法采集哨点医院的流感样病例（ILI）咽拭子标本,用荧光定量RT-PCR方法检测病毒核酸,对核酸阳性标本使用MDCK细胞进行病毒分离和血凝实验鉴定。结果共采集ILI咽拭子标本1 511份,检测出流感病毒核酸阳性标本125份,总阳性率为8.27%。其中季节性H1N1 0份,季节性H3N2 56份,新甲型H1N1 24份,B型30份,A未分型15份;男女性阳性率差异无统计学意义（χ2=0.04,P〉0.05）;4个年龄组中,25~岁组阳性率最低,为4.27%,60~岁组阳性率最高,为15.79%。结论2012年流感的流行主要集中在1~7月份,B型与季节性H3型交替出现,2013年流感流行出现两个高峰,主要以新甲型H1N1为优势毒株。Objective To analyze the results of etiology surveillance of influenza in Shaoguan from 2012 to 2013,and find out the etiology and epidemiology characteristics of influenza so as to provide scientific basis for influenza control and prevention. Methods The throat swab specimens of influenza-like illness were collected from the sentinel hospital for virus nucleic acid detection by fluorescence quantitative RT-PCR. MDCK cells were used to isolated the influenza virus and the subtype of isolated virus was identified by HA test. Results In total 1 511 specimens,125 samples were influenza virus positive, with a positive rate of 8.27%, 0 cases for the seasonal H1N1,56 cases for seasonal H3N2,24 cases for the new influenza A（H1N1）,30 cases for the influenza B and 15 for the non-typed of influenza A. The positive rate of virus had no statistical difference between the male and the female（χ2=0.04,P 〉0.05）.The lowest positive rate（4.27%） was in the age group of twenty-five and the highest positive rate（15.79%） was in the age group of sixty. Conclusion The epidemic of the influenza was from January to July in 2012.Influenza B and the seasonal H3N2 appeared alternately.there were two peaks in 2013,and the dominant subtype was the new influenza A（H1N1）.

关 键 词：流感 病原学监测 韶关 

分 类 号：R373.13[医药卫生—病原生物学]