泌尿生殖道支原体感染及耐药性分析  

Analysis of the prevalence of Mycoplasma infections and their drug resistance in the urogenital tract

作　　者：李仕伟[1] 傅雷[1] 刘艳秋[1] 

机构地区：[1]南京医科大学附属南京医院,江苏南京210006

出　　处：《现代预防医学》2015年第4期762-763,768,共3页Modern Preventive Medicine

摘　　要：目的了解医院门诊患者泌尿生殖道支原体感染情况及耐药性,为临床合理用药提供依据。方法采用培养法对门诊患者1 632例泌尿生殖道标本进行解脲支原体和人型支原体培养及药敏分析。结果支原体感染以单纯解脲脲原体感染为主,且女性感染率高于男性(P<0.05)。药敏结果显示,解脲脲原体对美满霉素、多西环素、交沙霉素及四环素敏感性最高,分别为97.3%、97.1%、90.2%及80.6%,人型支原体对红霉素、罗红霉素、阿奇霉素和克拉霉素耐药性最高,为100.0%。结论支原体是泌尿生殖道感染中一类很重要的病原菌且耐药性日益严重,临床医生应当依据药敏结果合理用药。Objective The study aimed to assess the prevalence of Mycoplasma infections and their drug resistance in the urogenital tract of infected patients, so to provide a reference for the rational use of antibiotics in clinical practices. Methods 1632 urogenital tract specimens were collected for culturing Mycoplasma urealytium and Mycoplasma hominis and analysis of their drug sensitivity. Results Most of the Mycoplasma infections were caused by Ureaplasma urealyticum; and female had a higher infection rate than male （P〈0.05）. Drug sensitivity test indicated that Ureaplasma urealyticum was most sensitive to minocycline （97.3%）, doxycycline （97.1%）, josamycin （90.2%）, and tetracycline （80.6%）, and that Mycoplasma hominis was most resistant against erythrocin, roxithromycin, azithromycin, and clarithromycin （100.0%）. Conclusion Mycoplasma is among the most important pathogenic bacteria in urogenital tract infections and its drug resistance has become a serious issue. Clinicians should practice rational antibiotics use according drug sensitivity results.

关 键 词：泌尿生殖道 解脲支原体 人型支原体 

分 类 号：R375[医药卫生—病原生物学]