EGF promotes mammalian cell growth by suppressing cellular senescence  

作　　者：Peter B Alexander Lifeng Yuan Pengyuan Yang Tao Sun Rui Chen Handan Xiang Jiekai Chen Haoyu Wu Daniel R Radiloff Xiao-Fan Wang 

机构地区：[1]Department of Pharmacology and Cancer Biology, Duke University Med- ical Center, Durham, NC 27710, USA [2]Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong 510530, China [3]Department of Pediatrics, University of British Columbia, Vancouver, V6T 1Z4, Canada

出　　处：《Cell Research》2015年第1期135-138,共4页细胞研究（英文版）

摘　　要：Dear Editor, Cellular senescence is a state of irreversible proliferative arrest that is believed to be an important determinant of both cancer development and organismal aging [1]. Although numerous molecules have been found to promote senescence, little is known about the nature of anti-senescent factors under physiological conditions.

关 键 词：表皮生长因子 细胞衰老 细胞生长 哺乳动物 机体衰老 生理条件 不可逆 多分子 

分 类 号：Q516[生物学—生物化学] Q255