夫西地酸乳膏联合丙酸氟替卡松乳膏治疗湿疹52例临床观察  

Clinical Observation of Fusidic Acid Cream Combined Fluticasone Propionate Cream in the Treatment of 52 Eczema Patients

作　　者：陈昭 黄科宇[2] 陈峥[3] 

机构地区：[1]河北省唐山市工人医院,河北唐山063000 [2]河北省开滦总医院,河北唐山063000 [3]河北省唐山市人民医院,河北唐山063000

出　　处：《中国皮肤性病学杂志》2015年第1期109-110,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的观察夫西地酸乳膏联合丙酸氟替卡松乳膏治疗湿疹的临床疗效及安全性。方法通过随机数字表法将入选的102例湿疹患者随机分为两组，治疗组52例，用夫西地酸乳膏和丙酸氟替卡松乳膏交替外涂于皮疹处，间隔时间约为1h，早、晚各一次。对照组50例，单用丙酸氟替卡松乳膏外搽，疗程14d10结果治疗组治疗第7天和第14天时有效率分别为50．00％为80．76％；对照组分别为46．00％和62．00％。仅治疗第14天时差异有统计学意义（P〈0．05）。治疗过程中均未出现严重的不良反应，未经特殊处理均于1—5d消失。结论夫西地酸乳膏联合丙酸氟替卡松乳膏治疗湿疹效果较好，且无明显不良反应。Objective To observe the efficacy and safety of fusidic acid cream combined fluticasone propionate cream in the treatment of eczema. Methods According to random number table, 102 patients were divided into two groups. Fifty-two patients of treatment group were treated with fusidic acid cream and fluticasone propionate cream, twice a day with an interval of 1 hour. Fifty patients of control group were treated with fluticasone propionate cream alone. Two groups were followed up for 14 days. Results Effective percentage of treatment group on the 7th day, 14th day were 50.00% , 80.76% , while that of the control group were 46.00%, 62.00%. Statistical significance of the effective percentage was found between the two groups on 14th day （χ2 = 4.41, P 〈 0.05 ）. No serious adverse reactions occurred during the treatment, and disappeared within 1 to 5 days. Conclusion The use of fusidic acid cream combined fluticasone propionate cream in the treatment of eczema is effective and safe.

关 键 词：夫西地酸 丙酸氟替卡松 湿疹 临床观察 

分 类 号：R758.23[医药卫生—皮肤病学与性病学]