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机构地区:[1]辽宁省沈阳市第四人民医院干诊内科,110016 [2]中国医科大学附属第一医院循环内科
出 处:《中国综合临床》2015年第1期1-3,共3页Clinical Medicine of China
基 金:辽宁省科技厅科学技术计划项目(2012225084)
摘 要:目的探讨急性心肌梗死(AMI)并发室间隔穿孔(VSP)的临床特征以及不同治疗方法的预后。方法回顾性总结沈阳市第四人民医院、中国医科大学附属第一医院循环内科2000年6月至2014年5月救治的57例AMI+VSP患者的临床资料,评估治疗方法及预后。结果57例AMI+VSP患者中,前壁心肌梗死43例(75.4%),非前壁心肌梗死14例(24.6锈);超声心动图显示左心室舒张末期内径(53.7±9.5)mm,左心室射血分数(48.5±11.8)%。VSP直径(9.8±7.9)mm;VSP位于心尖及心尖附近37例(64.9%);肌钙蛋白I为(16.7±12.9)μg/L,c反应蛋白为(99.7±31.4)mg/L,N末端B型利钠肽为(3051.Z±879.7)μg/L。57例患者中30d死亡41例(71.9%),1年死亡45例(78.9%);保守治疗23例中,30d死亡17例(73.9%),1年死亡21例(91.3%);手术治疗34例,30d死亡22例(64.7%),1年死亡26例(76.5%)。结论AMI+VSP以高病死率为特点,发病部位多近心尖部,内科保守治疗病死率高,早期外科手术治疗可降低病死率。Objective To investigate the clinical characteristics and prognosis of acute myocardial infarction(AMI) combined with ventrical septal perforation (VSP). Methods Fifty-seven AMI + VSP patients were retrospectively analyzed their clinical characteristics and outcomes who were treated in the Fourth People' s Hospital of Shenyang and the First Hospital Affiliated to China Medical University from June 2000 to May 2014. Results Of all patients, 43 ( 75.4% ) VSP occurred anterior wall AMI, and 14 ( 24. 6% ) were not. Echocardiogram show the end diastolic diameter of left ventricle was ( 53. 7± 9. 5 ) mm, left ventricle ejection fraction was ( 48.5 ± 11.8 ) %, VSP diameter was ( 9. 8 ± 7.9 ) mm, and 37 ( 64.9% ) were with near apex. The level of cardiactroponin I, C-reactive protein, and N terminal of B type natriuretic peptide of patients were ( 16. 7±12. 9 ) μg/L, ( 99.7 ±31.40 mg/L, ( 3 051.2± 879.7 )μg/L Total mortality was 71.9% (41/57) in 30 days and 78. 9% (45/57) in 1 year. The mortality of operation group was 73.9% (17/23) in 30 days and 91.3% (21/23) in 1 year. The mortality of consecutive therapy was 64. 7% (22/34) in 30 days and 76. 5% (26/34) in 1 year. Conclusion The mortality of AMI + VSP is higher and operation is the most effective therapeutic method.
分 类 号:R542.22[医药卫生—心血管疾病]
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