2012-2013年儿童医院主要病原菌分布及耐药性变迁  

The Distribution and Drug Tolerance Change of the Main Pathogenic Bacteria in Children's Hospital Kaifeng in 2012-2013

作　　者：董懿珍 张伟 张胜安 任贵香 薛静 

机构地区：[1]河南省开封市儿童医院,河南开封475000

出　　处：《中国医学创新》2015年第3期112-114,共3页Medical Innovation of China

基　　金：常州四药临床药学科研基金(CZSYJJ110304)

摘　　要：目的:了解近2年某儿童医院主要病原菌分布情况及对常用抗菌药物耐药性变迁,为儿科临床合理选择抗菌药物提供依据。方法:收集2012-2013年本院细菌实验室相关数据,统计主要病原菌的检出率、耐药率,对耐药率明显变化的病原菌进行字2检验。结果:近2年儿童医院检出主要病原菌均以革兰染色阴性杆菌为主,革兰染色阴性杆菌对各类抗菌药物耐药率均有不同程度升高;而铜绿假单胞菌对大部分抗菌药物耐药率升高明显(P<0.05)。结论:近2年儿童医院院内感染菌的分布和耐药率有一定变化,特别是铜绿假单胞菌耐药率有升高趋势,提示儿童医院院内感染菌非发酵菌及其耐药率有上升趋势,应加强控感管理,合理使用抗菌药物。Objective：To realize the distribution and drug tolerance change of the main pathogenic bacteria in children＇s hospital of the two years, and provide a basis to logical choice of the antibacterial for clinic. Method：The data of bacteriological lab from 2012 to 2013 were collected and the detection rate, tolerance rate of the pathogenic bacteria were summed. And made a chi-square test to the bacteria whose tolerance rate varying obviously.Result：The main pathogenic bacteria in children＇s hospital were gram negative bacteria of the last two years. The tolerance to antibacterial of the gram negative bacillus was increased. The tolerance of pseudomonas aeruginosa was increased visibly（P〈0.05）.Conclusion：There are some changes of pathogenic bacteria＇s distribution and drug resistance in children＇s hospital for last two years. The drug resistance of pseudomonas aeruginosa is increased. That means non-fermentative bacterial and tolerance in children＇s hospital are upward. We shall reinforce managing controlling infection and intelligent using antibacterial.

关 键 词：儿童 细菌耐药监测 耐药率 

分 类 号：R197.5[医药卫生—卫生事业管理]