基于Consort声明和改良Jadad量表评价中药治疗原发性骨质疏松症  

Accessing on Chinese Herb Therapy for Primary Osteoporosis Using the Consort Statment and improved Jadad Scale

作　　者：马少华[1] 李同林[1] 马勇[2] 

机构地区：[1]南京中医药大学骨伤研究所,南京210029 [2]江苏省中医院骨伤科

出　　处：《中国中医骨伤科杂志》2015年第1期22-25,共4页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：康缘中医药科技创新与奖励基金项目(HZ1004KY)

摘　　要：目的：探讨采用Consort声明及改良Jadad量表评价中药治疗原发性骨质疏松症临床随机对照试验（RCT）的报告质量。方法：计算机检索中国知网（CNKI）、中国生物医学文献数据库（CBM）、维普（VIP）、万方四个数据库,手工检索所有中医药类核心期刊及纳入文献的参考文献,对纳入的44篇文献采用Consort声明及改良Jadad量表进行质量评价。结果：根据Consort全部22条评价条目,纳入分析的44篇文献中,32篇文献描述了患者基线数据及临床特征,8篇阐述了随机分配的方法,尚无文献提及样本量的计算及分配隐藏,2篇采用盲法。根据改良Jadad量表评价44篇文献0~3分的有37篇,4~7分的7篇。结论：目前国内关于中药治疗原发性骨质疏松症的临床随机对照试验文献质量普遍较低,呼吁今后采用国际公认Consort声明和改良Jadad量表对中药治疗原发性骨质疏松症RCT进行规范化实施及报道。Objective： To access the reporting quality of randomized controlled trials （RCTs） on Chinese herb therapy for Primary osteoporosis by Consort statement and improved Jadad scale. MethodS： Four databases including the CNKI, CBM, VIP and WanFang （2009~2014） were searched systematically by using internet. Handsearch for journals about all core traditional medicine peridoical and future reference were conducted. Accessing the reporting quality of 44 RCTs by u- sing the Consort Statment and improved Jadad scale. Results： In regard to the items in the Consort statments, 32RCTs described baseline demographic and clinical characteristics, 8RCTs described the method of generating the random se- quence, 2 RCTs used blinding and no RCT reported the method to calculate the sample size. In regard of the improved Jadad scale, 37 reports scored 0~3 points and 7 reports scored 4-7 points. Conclusion： Currently, the quality of domestic RCTs on Chinese herb therapy for Primary osteoporosis are still low and the Consort Statment and improved Jadad scale should be used to standardize the reporting RCTs of Chinese herb therapy for Primary osteoporosis.

关 键 词：中药 原发性骨质疏松 CONSORT声明 Jadad量表 

分 类 号：R681[医药卫生—骨科学]