胰岛素样因子3研究进展  

Progresses of insulin-like factor 3

作　　者：龚艳[1] 李嫔[1] 

机构地区：[1]上海交通大学附属儿童医院上海市儿童医院内分泌科,200040

出　　处：《国际儿科学杂志》2015年第1期35-38,共4页International Journal of Pediatrics

摘　　要：胰岛素样因子3属于胰岛素超家族松弛素亚族，是睾丸间质细胞分泌的主要产物，其合成完全依赖睾丸间质细胞的分化状态。胰岛素样因子3除了在睾丸下降方面起重要作用，对于评估睾丸间质细胞功能也很敏感，有很大的临床价值。胰岛素样因子3在生殖细胞存活、骨代谢调控中发挥重要作用。Insulin-like factor 3 belongs to the insulin superfamily relaxin subfamily. Insulin-like factor 3 is the main product secretion of leydig cells, and its synthetic process totally relies on the state of leydig cells differentiation. Insulin-like factor 3 plays an important role in testicular descent, and has a great clinical value for evaluating function of leydig cells. Meanwhile, insulin-like factor 3 is deemed to play an important role in germ cell survival and regulation of bone metabolism.

关 键 词：胰岛素样因子3 睾丸间质细胞 隐睾 环境内分泌干扰物 

分 类 号：R3416[医药卫生—基础医学]