脾氨肽联合阿维A和鸦胆子在扁平疣治疗中的应用  

Application of Spleen Aminopeptide joint Avermectin A and Brucea Javanica in the Yreatment of Verruca Planae

作　　者：唐淑洁[1] 张佳琦[1] 张华[1] 刘洋[1] 张丽[1] 

机构地区：[1]齐齐哈尔医学院第一附属医院,黑龙江齐齐哈尔161041

出　　处：《中国医药指南》2015年第3期46-47,共2页Guide of China Medicine

摘　　要：目的观察脾氨肽口服冻干粉联合阿维A胶囊和鸦胆子治疗扁平疣的临床疗效。方法将102例扁平疣患者随机分成两组。治疗组51例,对照组51例。两组患者均口服阿维A胶囊每日一次,每次20 mg,疣体外敷去壳捣碎的鸦胆子。治疗组同时口服脾氨肽冻干粉,每日一次,每次2 mg。治疗4周、8周观察疗效。结果治疗组治疗4周、8周的有效率分别是78.43%和92.16%。对照组分别为56.86%和70.59%,两组患者治疗4周、8周的有效率比较有统计学意义(P<0.05),且治疗组的复发率明显低于对照组(P<0.05)。结论脾氨肽口服冻干粉联合阿维A胶囊和鸦胆子治疗扁平疣的临床疗效确切,复发率非常低。Objective To observe the clinical effect of spleen aminopeptide oral freeze- dried powder combined with acitretin capsules and brucea javanica in the treatment of verruca planae. Methods 102 patients with cases of Vemlca planae were divided randomly into two groups. 51 cases were in treatment group, 51 cases were in control group. The patients of two groups both were treated with oral acitretin capsules once a day, 20 mg each time, applicate external peeled and mashed brucea javanica on verrucous body. The patients of treatment group were given oral administration of spleen aminopeptide freeze-dried powder, once a day, each time 2 rag. We evaluated the efficacy in the forth and eighth week. Results The effective rates in treatment group were 78.43% and 92.16%, and the control group were 56.86% and 70.59% respectively. The totle effective rates were significan between the two groups of patients in the forth and eighth week （P〈0.05）, and the recurrent rate in treatment group was obviously lower than control group （P〈0.05）. Conclusion The clinical effect of spleen aminopeptide oral freeze dry powder joint acitretin capsules and brucea javanica in the treatment of verruca planae, and the recurrence rate is very low.

关 键 词：脾氨肽口服冻干粉 阿维A胶囊 鸦胆子 扁平疣 应用 

分 类 号：R752.52[医药卫生—皮肤病学与性病学]