123例重型β地中海贫血患儿输血治疗状况的调查  

Blood Transfusion Therapy for Severe β-thalassemia Children

作　　者：刘兴玲[1] 吴月勤[2] 李惠森 吴勇[2] 陈宝婵[2] 刘艳[2] 吴远军[2] 

机构地区：[1]南方医科大学附属东莞市石龙人民医院,广东东莞523326 [2]中山大学附属东华医院,广东东莞523110

出　　处：《护理学报》2014年第23期19-22,共4页Journal of Nursing（China）

摘　　要：目的 了解重型β地中海贫血患儿的输血治疗状况,以指导对重型β地中海贫血患儿家庭的健康教育及人文关怀.方法 调查123例重型β地中海贫血患儿第1次输血治疗时的年龄、每次启动输血时的血红蛋白（Hb）值、每次输血治疗剂量、持续输血治疗时间、已输血总量及终止输血治疗情况.结果 123例重型β地中海贫血患儿第1次输血时的年龄在0-3岁者118例,＞3-18岁者5例;第1次启动输血时的Hb均值为（53.23±12.61）g/L;15例患儿只接受过1次输血治疗,108例接受多次输血治疗的患儿启动输血治疗时的Hb均值为（75.15±14.24）g/L,其中接受持续规范输血治疗者仅36例（29.3％）;123例患儿在调查的6年间平均持续输血治疗时间为645 d,平均输注红细胞总量38.96U;持续接受输血治疗的患儿年均输血量在9岁以前随年龄的增长而逐年增加,在9岁以后反而呈下降的趋势;123例重型β地中海贫血患儿中已终止输血者47例,终止输血时的年龄在10岁以内者42例,超过10岁5例,6岁以内的患儿年龄越小终止输血治疗的比率越高.结论 多数重型β地中海贫血患儿没能接受持续规范的输血治疗,有必要对重型β地中海贫血患儿的家庭进行正确的健康教育及人文关怀,指导、帮助重型β地中海贫血患儿接受规范的输血治疗,以提高患儿的生存期及生存质量.Objective To investigate the application of blood transfusion therapy in severe β-thalassemia children,and provide guidance for health education and humanistic care for families with severe β-thalassemia children.Methods Totally 123 cases of β-thalassemia children were investigated about their ages at first blood transfusion treatment,Hb value every time they started blood transfusion,dose,treatment duration,the total blood transfusion amount,and their status when blood transfusion treatment ended.Restults Of the total,118 cases began their first blood transfusion treatment before 3 and only 5 cases over 3 with the average blood Hb value of （53.23±12.61）g/L.Fifteen cases had only received the treatment once,and 108 cases receiving the blood transfusion treatment for many times began their treatment when the Hb value was （75.15±14.24）g/L but only 36 cases （29.3％） had received regular blood transfusion treatment persistently; In 123 cases,the average duration of the transfusion treatment was 645 days,and the average amount of red cell transfusion 38.96 units; for those with persistent blood transfusion treatment,the annual blood transfusion amount rose with the increase of their age before 9,but decreased after 9.Forty-seven cases had ended their transfusion treatment and 42 cases before 10 years old while 5 cases over 10,and for those younger than 6,the younger the children,the higher percentage they stopped their transfusion treatment.Conclusion Most children with severe β-thalassemia have not received regular and continual blood transfusion therapy.It is necessary to give health education and humanistic care to families with severe β-thalassemia children and guide them to take regular and continual blood transfusion treatment to improve their lifetime and quality of life.

关 键 词：地中海贫血 输血 护理 

分 类 号：R725.5[医药卫生—儿科]