185例新生儿围术期输血回顾性分析  

Retrospective analysis of perioperative blood transfusion in 185 neonates

作　　者：王亮[1] 陈贝贝[1] 崔洁[1] 唐文[1] 

机构地区：[1]重庆医科大学附属儿童医院麻醉科 儿童发育疾病研究教育部重点实验室 儿科学重庆市重点实验室 重庆市儿童发育重大疾病诊治与预防国际科技合作基地,重庆400014

出　　处：《中国输血杂志》2014年第12期1329-1332,共4页Chinese Journal of Blood Transfusion

基　　金：国家临床重点专科建设项目资助(国卫办医涵[2013]544号)

摘　　要：目的了解肠切除肠吻合术新生儿术中输血现状、术中输血的影响因素及其对预后的影响。方法回顾性分析2010～2013年间于重庆医科大学附属儿童医院行剖腹探查、肠切除肠吻合术新生儿病历资料185例,按照是否有术中输血,分为输血组和非输血组。可疑的影响因素进行组间比较后,将差异有统计学意义的因素进行多因素logistic回归分析,筛选新生儿术中输血的影响因素;并分析不同贫血严重程度新生儿术中输血对预后的影响。结果术中输注悬浮红细胞96例,输注率为51.89%。logistic回归分析显示,术前Hb浓度、术中出血量、手术时间是新生儿术中输血的影响因素。中度贫血、轻度贫血、非贫血新生儿术中输血未能明显改善预后。结论术前Hb浓度、术中出血量、手术时间是新生儿术中输血的独立影响因素;术中轻度、中度贫血对新生儿预后无明显影响,可不予输血治疗。Objective To understand the intraoperal：ive transfusion status, the risk factors associated with intraoperal：ive blood transfusion and the prognosis in neonates undergoing inles- final resection and anastomosis surgery. Methods Medical re- cords of 185 neonates who received intestinal resection and arastomosis surgery in Children＇s Hospital of Chongqing Medical University from January 2010 to December 2013 were collected and retrospectively analyzed. The neonates were divided into blood transfusion group and non-transfusion group according to whether or not they had received intraoperative blood transfusion. Univariate analysis and multivariate logistic regression anal- ysis were used to investigate the risk factors of intraoperative blood transfusion. The relationship between the intraoperative blood transfusion of neonate with different degree of anemia and prognosis also was analyzed. Results Of the 185 neonates in the study, 96 （51.89%） received transfusion. Multivariate logistic regression analysis indicated that the risk factors of in- traoperative blood transfusion were preoperative Hb concentration, intraoperative blood loss and operation time. Intraoperative blood transfusion for neonates with moderate, mild and no anemia failed to significantly improve the prognosis. Conclusion After adjusting for other potential variables, preoperative Hb concentration, intraoperative blood loss and operation time were the independent predictors of intraoperative blood transfusion in neonate undergoing intestinal resection and anastomosis sur- gery. Mild-to-moderate anemia of neonate appeared not to contribute to a bad prognosis, indicating no need for transfasion.

关 键 词：新生儿 贫血 围术期/输血 回顾性分析 

分 类 号：R457.1[医药卫生—治疗学] R722.6[医药卫生—临床医学]