儿童急性鱼胆中毒的临床特征及治疗  

Clinical Manifestations and Treatment of Child Acute Fish Bile Poisoning

作　　者：毛晓燕[1] 周太光[1] 

机构地区：[1]泸州医学院附属医院儿一科,四川省泸州市646000

出　　处：《中国全科医学》2014年第35期4248-4249,4252,共3页Chinese General Practice

摘　　要：目的总结儿童急性鱼胆中毒的临床特征及治疗方式。方法选取2013—2014年泸州医学院附属医院儿科收治的急性鱼胆中毒患儿3例,回顾性分析患儿临床表现、治疗方法、治疗效果及预后。结果患儿均表现为持续剧烈腹痛,以剑突下疼痛为主;伴呕吐,头晕,头痛;实验室检查提示ALT、AST均超出参考范围,伴重度肝功能损害。患儿入院后立即给予血液灌流(HP)结合内科综合治疗。治疗后,患儿ALT、AST、尿素氮(BUN)、凝血酶原时间(PT)出院时均恢复正常,随访未发现肝肾功能异常及深静脉血栓形成等后遗症。结论急性鱼胆中毒可导致患儿重度肝功能损害,尽早行HP结合内科综合治疗是抢救患儿中毒有效的治疗方式。Objective To analyze the clinical manifestations and its treatment of acute fish bile poisoning in children.Methods The clinical manifestations,laboratory examinations,treatment and results of 3 children with acute fish bile poisoning admitted to the Affiliated Hospital of Luzhou Medical College from 2013 to 2014 were analyzed and relevant literatures reviewed.Results All of the patients had lasting severe abdominal pains,mainly subxiphoid pains,complicated by vomiting,dizziness,headache. By laboratory tests,ALT and AST exceeded the reference range,with severe liver damage. The children were given hemoperfusion（ HP） combined with comprehensive medical treatment immediately after admission. The ALT, AST, BUN,prothrombin time were normal at discharge. No hepatorenal dysfunction,deep venous thrombosis or other sequelae occurred in the follow-ups. Conclusion Acute fish bile poisoning can cause severe liver damages in children. Early HP with comprehensive medical treatments is an effective therapeutic method.

关 键 词：儿童 鱼胆中毒 血液灌流 

分 类 号：R720.597[医药卫生—急诊医学]