原发全面性癫的神经放射学研究进展  

Progress in neuroimaging of idiopathic generalized epilepsy

作　　者：黄育斌[1,2] 张志强[1,2] 卢光明[1,2] 

机构地区：[1]南方医科大学南京临床学院 [2]南京军区南京总医院医学影像科,南京210002

出　　处：《国际医学放射学杂志》2014年第6期519-522,527,共5页International Journal of Medical Radiology

基　　金：国家自然科学基金项目(81271553)

摘　　要：原发全面性癫病人大脑无器质性病变,常规MRI检查无法发现异常。目前普遍认为病人皮质-丘脑网络存在微细结构及功能上的异常改变,这种异常改变在原发全面性癫的发病中起着重要作用。多模态影像技术联合应用可从结构、功能、血流及代谢等方面观测皮质-丘脑异常,为研究原发全面性癫的病理生理学机制提供方法。就原发全面性癫皮质-丘脑网络的神经放射学研究进展进行综述。Patients with idiopathic generalized epilepsy present no abnormalities in routine MRI. It is currently proposed that abnormal structural and functional changes in corticothalamic network play important roles in the pathogenesis of idiopathic generalized epilepsy. Multi-modality neuroimaging can provide information of structure, cerebral blood flow and metabolism of human brain, and can be used to investigate the mechanism of idiopathic generalized epilepsy. The research progresses of corticothalamic network in neuroimaging were reviewed in this article.

关 键 词：原发全面性癫 日 丘脑 皮质 多模态 神经影像 

分 类 号：R445.2[医药卫生—影像医学与核医学]