沈阳市2010—2013年疑似预防接种异常反应监测分析  

Analysis on the Surveillance of Suspect Adverse Events Following Immunization in Shenyang from 2010 to 2013

作　　者：高冬梅[1] 贾妮娜[1] 刘宝义[1] 

机构地区：[1]沈阳市疾病预防控制中心,沈阳110031

出　　处：《中国初级卫生保健》2014年第12期74-75,共2页Chinese Primary Health Care

摘　　要：目的 分析预防接种疑似异常反应（AEFI）的发生特征,评价AEFI信息管理系统运行状况和疫苗免疫的安全性. 方法 用描述性流行病学方法分析2010-2013年沈阳市疑似异常反应信息管理系统的数据.结果 沈阳市2010-2013年共报告AEFI 883例,其中一般反应824例（93.3％）,异常反应36例（4.1％）,偶合症23例（2.6％）.AEFI发生率最高的是麻风疫苗,为66.17/10万剂次,0～2岁组儿童发生AEFI最多,占75.1％.AEFI报告完整率达100％,48 h内及时报告率和调查率均为100％.结论 AEFI报告质量和疫苗安全性良好,全市AEFI监测的完整性较好,报告和调查的及时性较好,个别地区的报告敏感性有待于提高.OBJECTIVE To analyze the features of the suspect adverse events following immunization（AEFI） in Shenyang. To evaluate the report quality of the Information Management System and the safety of vaccines. METHODS Descriptive epidemiological methods were used to analyze the AEFI cases reported by AEFI information management system from 2010 to 2013. RESULT A total of 824 AEFI cases were reported in Shenyang from 2010 to 2013, including 824（93.3%）genneral reaction cases, 36（4.1%） adverse reaction cases, 23（2.6%）coincident cases. The highest rate of AEFI was caused by measles and rubella vaccine, which reported AEFI rate was 66.17 per 10 million doses. The most AElCI cases were happened in 0-2 years old group, acounted for 75.1%. The reported integrity rate reached 100%, the timely report rate in 48 hours was 100%, the timely report rate in 48 hours was 100%. CONCLUSION The study showed that the quality of AEFI reported and the safety of vaccines were satisfactory.The integrality and timelinessrates of surveillance system were good. But that deed to be improved as well. The sensitivity of AEFI surveillance was still low.

关 键 词：疫苗 疑似预防接种异常反应 监测 沈阳 

分 类 号：R186[医药卫生—流行病学]