胃癌前期病变中医病机的研究概况  

Research Review on Pathogenesis in TCM of Precancerous Lesions of Gastric Cancer

作　　者：曹婷婷[1] 叶柏[2] 

机构地区：[1]南京中医药大学第一临床医学院,南京210023 [2]江苏省中医院消化科,南京210029

出　　处：《光明中医》2014年第12期2682-2683,共2页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：江苏省中管局课题支撑项目(No.JD11039)

摘　　要：胃癌前期病变(Precancerous lesions of gastric cancer,PLGC)是病理学概念,是指更容易发生癌变的组织病理变化,癌前病变主要是指中、重度的异型增生和不完全性结肠型肠化生。目前,中医对PLGC的病机多样性的辨证已渐趋一致,认为主要是本虚标实,本虚为病之根本,以脾胃气阴两虚为主,标实则有气滞、血瘀、热毒等,其病位主要在脾胃,与肝相关联。但另一方面,仍缺少对PLGC中医证候、治疗方法的流行病学调查,也未得到临床长期的追踪和微观检验的肯定。故促进PLGC中医病因病机的研究,推动PLGC中医辨证标准化、规范化,找出疗效确切、便于推广的中医治疗方药,仍然任重道远。Precancerous lesions of gastric cancer（PLGC） is a pathological conception. It indicates a pathological change that is susceptible to canceration. PLCC generally incorporates medium and severe dysplasia and incomplete colic intestinal metaplasia. Currently, Traditional Chinese Medicine （TCM） holds a basic consensus on syndrome differentiation of muhiple pathogenesis of this disease. It believes the genuine deficiency is the root of the cause, especially the deficiency of qi and yin of spleen and stomach. While the pathogenic factor involves qi stagnation, blood stasis and heat toxicity and so on. The pathological organs relate to spleen and stomach, and have a relationship with liver. On the other hand, it still lack the epidemiological survey of the syndromes and treatment methods of PLCC. Also it is far away from the certification of long-term tracking and micro-examination. So it is significance to promote the research of the cause and pathogenesis in TCM of PLCC and create a standardization and normalization of syndrome differentiation to find a valid formula with good therapeutic effect.

关 键 词：胃癌前期病变 中医病机 胃脘 口嘈杂 

分 类 号：R259[医药卫生—中西医结合]