基于混沌信号的经皮神经电刺激仪的设计  

Design of Transcutaneous Nerve Electric Stimulation Instrument Based on the Chaotic Signal

作　　者：郑金存[1] 张慧[2] 梁伟江[3] 聂国朝[3] 陈铁军[1] 王洪乾[4] 

机构地区：[1]玉林师范学院电子与通信工程学院,广西玉林537000 [2]玉林师范学院生命科学与技术学院,广西玉林537000 [3]玉林师范学院纳米医药中心,广西玉林537000 [4]玉林市红十字会医院,广西玉林537000

出　　处：《中国医学物理学杂志》2015年第1期86-91,共6页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(81260227);广西科技攻关计划项目(1298003-2-11);广西教育厅项目(201203YB154;2013YB198);玉林师范学院校级重点项目(2014YJZD04)

摘　　要：传统的电刺激仪器都是采用三角波、方波与非对称波等信号作为刺激信号源,或是将一些特定的信号先进行存储、然后再输出作为信号源,这些信号都呈现出周期性,作用于人体时容易使人产生适应性,随着刺激次数的增多而使效果逐渐变差,论文设计了一个基于混沌模型的非周期信号的电刺激系统。首先是在MATLAB软件的Simulink平台下构建出混沌模型,然后借助于DSP Builder软件将混沌模型转换为FPGA的工程文件,通过Simulink平台的模型仿真及Modelsim软件的行为级仿真,仿真无误后将工程文件在Altera公司的开发平台Quartus软件下进行编译、综合,最后生成可执行文件,下载到FPGA芯片即产生了混沌信号;将信号进行电压放大,功率放大,接入电极,实现了基于混沌信号的电刺激系统。所设计的系统获得了新型的电刺激效果,通过改变混沌方程的参数以及改变信号的输出频率,可以改变刺激时的直观感觉,由于人体的生物信号本身具有复杂的混沌特性,用它作用于人体所具有的更深层次的生物效应还需更多的探索研究。Objective The three signals periodic triangle wave, square wave, and asymmetric wave, and the specific store-output signal are often used in the conventional electrical stimulation instruments as the stimulus sources. However, the periodic signal is easy to produce adaptation in the treatment whose effect will decrease gradually with the increasing times. To work well in electric stimulation, we designed a novel system based on the non-periodic chaotic signal. Methods Building a chaotic model in the Simulink of MATLAB was the first step. Then the model was converted into the FPGA project file by using the DSP Builder software. And the file was simulated under the Simulink and Modelsim. After the correction, the file was compiled and synthesized. Finally the executable file was downloaded into the FPGA chip and the chaotic signal was generated. Electrical stimulator was created when the voltage and power of the chaotic signal had been amplified. Results A novel stimulus effect is achieved by using the stimulator based on the chaotic signal. And the stimulus effect can be changed by the varied Chaotic parameters. Conclusion The electrical stimulation instrument based on the chaotic signal changes the design concept of the traditional stimulation instrument. It is necessary to carry out more experiments to apply in the biological effect of human-beings because of the chaos of biological signals.

关 键 词：经皮神经电刺激 电刺激仪 混沌信号 FPGA 

分 类 号：R318.6[医药卫生—生物医学工程]