糖尿病对乳腺癌患者生命质量的影响  

Impact of diabetes mellitus on quality of life in patients with breast cancer

作　　者：王继伟[1] 宫霄欢[1] 陈学芬[1] 石常宏[1] 孙丽[1] 张庆云[1] 罗正年 袁正平 余金明[1] 

机构地区：[1]复旦大学公共卫生学院健康行为与健康教育教研室、公共卫生安全教育部重点实验室,上海200032 [2]上海市健康教育协会 [3]上海市癌症康复俱乐部

出　　处：《中华内分泌代谢杂志》2015年第1期43-46,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：国家社会科学基金青年项目（13CSH076）;上海市公共卫生重点学科建设计划资助项目（12GWZX0901）;上海市卫生和计划生育委员会委级科研项目（20134068）

摘　　要：目的 研究糖尿病与乳腺癌患者生命质量的关系,为糖尿病和乳腺癌患者生命质量的综合改善提供依据.方法 2013年4月至7月在上海进行横断面研究,3 344例女性社区乳腺癌患者接受问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、糖尿病患病情况等,以欧洲癌症研究与治疗组织QOL量表C30（EORTC QLQ-C30）中文版和癌症治疗功能评估量表（FACT-G）中文版分析受试者的生命质量.比较患和未患糖尿病的乳腺癌患者生命质量的组间差异.结果 在所有被调查的乳腺癌患者中同时患有糖尿病者为14.38％.对于EORTC QLQ-C30量表,患糖尿病者的躯体功能、角色功能、认知功能、情绪功能、社会功能及总体健康状况得分均显著低于未患糖尿病者的相应得分（P＜0.05）,而在疲倦、恶心呕吐、疼痛、气促、失眠、食欲丧失、便秘等生理及症状维度以及经济困难领域患糖尿病者得分均高于未患糖尿病者,且大部分均有显著性差异.对于FACT-G量表,未患糖尿病者的生理状况、社会状况、情感状况、功能状况4个维度得分以及FACT-G总分均显著高于糖尿病患者的相应得分（P＜0.05）.结论 糖尿病影响乳腺癌患者的生命质量,应采取慢性病综合管理措施以提高糖尿病和乳腺癌患者的生命质量.Objective To investigate the impact of diabetes on quality of life in breast cancer patients.Methods A cross-sectional study was conducted among 3 344 community patients suffering from breast cancer during April to July 2013,in Shanghai.Data were collected using a questionnaire,which included socio-demographic situation,diagnosis,and treatment of cancer,as well as diabetes mellitus.European Organization for Research and Treatment of Cancer QOL Questionnaire-C30 （EORTC QLQ-C30） Simplified Chinese Version and Functional Assessment of Cancer Therapy （FACT-G） Simplified Chinese Version were used to investigate the quality of life in the patients.The quality of life scores in breast cancer patients with and without diabetes were compared.Results The prevalence of diabetes was 14.38% in the patients with breast cancer.Breast cancer patients without diabetes reported significantly higher EORTC QLQ-C30 scores in physical functioning,role functioning,cognitive functioning,emotional functioning,social functioning,global health,lower EORTC QLQ-C30 scores in fatigue,pain,dyspnoea,insomnia,appetite loss,constipation,diarrhoea,and higher FACT-G scores in physical well-being,social/family well-being,emotional well-being,functional well-being,compared with the patients with diabetes （P 〈 0.05）.Conclusions Diabetes mellitus affects the quality of life in patients with breast cancer.Integrated measures for chronic disease management should be taken to improve the quality of life in patients with breast cancer as well as diabetes mellitus.

关 键 词：糖尿病 乳腺癌 生命质量 

分 类 号：R587.1[医药卫生—内分泌] R737.9[医药卫生—内科学]