血清血管生成素样蛋白2水平与2型糖尿病大血管并发症的相关性研究  

The association between serum Angptl 2 and macrovascular complications in type 2 diabetes mellitus

作　　者：杜幸[1] 谢莹[1] 宗海军[1] 黄韵[1] 肖文金[1] 

机构地区：[1]苏州大学附属第二医院内分泌科,215004

出　　处：《中华内分泌代谢杂志》2015年第1期52-54,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：本文主要探讨人血清血管生成素样蛋白2（Angptl 2）是否与2型糖尿病大血管并发症相关.研究发现对照组、2型糖尿病有或无颈动脉粥样硬化组的血清Angptl 2浓度有统计学差异[0.98（0.82～1.22）、3.70（2.69 ～4.85）、1.17（0.76～ 2.47） ng/ml].Logistic回归显示血清Angptl 2作为独立因素影响2型糖尿病患者大血管并发症的发生发展.[Summary] This paper was to investigate whether serum angiopoietin-like protein 2 （Angptl 2） is associated with macrovascular complications in type 2 diabetes mellitus.The results showed that there were statistically significant differences in serum Angptl 2 levels among control group and groups of type 2 diabetic patients with or without carotid atherosclerosis [0.98 （0.82-1.22）,3.70 （2.69-4.85）,1.17 （0.76-2.47） ng/ml].Logistic regression showed that Angptl 2 was an independent risk factor of macrovascular complications in the patients with type 2 diabetes.

关 键 词：糖尿病 2型 动脉粥样硬化 血管生成素样蛋白2 

分 类 号：R587.2[医药卫生—内分泌]