产妇会阴侧切感染的病原学分析与抗菌药物优化治疗  

Maternal episiotomy infection etiology analysis and optimization of antimicrobial therapy

作　　者：赵丽[1] 张海燕[1] 王桂兰[2] 

机构地区：[1]胜利石油管理局妇幼保健院妇产科,山东东营257061 [2]胜利石油管理局胜北医院妇产科,山东东营257064

出　　处：《中华医院感染学杂志》2015年第4期917-919,共3页Chinese Journal of Nosocomiology

基　　金：山东省卫生厅基金资助项目(SW-2010B020)

摘　　要：目的探讨产妇会阴侧切分娩感染病原菌分布及耐药性,并及时应用敏感抗菌药物,提高临床治疗水平。方法随机选取2011年1月-2013年3月295例会阴侧切分娩产妇为研究对象,对其中发生医院感染的产妇进行病原菌和耐药性分析,研究数据采用SPSS16.0统计软件进行处理。结果 295例会阴侧切分娩产妇发生医院感染24例,感染率为8.14%,共分离出病原菌37株,其中革兰阴性菌占59.46%,革兰阳性菌占40.54%;革兰阴性菌对利福平、亚胺培南、美罗培南的耐药率为0,对其他抗菌药物耐药率均>42.86%,革兰阳性菌对替考拉宁、万古霉素耐药率为0,对其他抗菌药物耐药率均>50.00%;治疗后总有效率为91.67%。结论会阴侧切分娩产妇感染病原菌以革兰阴性菌为主,选择敏感抗菌药物治疗预后较好。OBJECTIVE To investigate maternal childbirth episiotomy infection and drug-resistant pathogens,and apply sensitive antimicrobial drugs in time,to improve the level of clinical treatment.METHODS Totally 295 cases of episiotomy birth mothers were randomly selected from Jan.2011 to Mar.2013 for study,and pathogenic bacteria and drug resistance of infected maternals were analyzed.The research data were processed by SPSS 16.0statistical software.RESULTS Of 295 episiotomy childbirth puerpera,there were 24 cases of co-infection,with the infection rate of 8.14%.A total of 37 pathogenic bacteria were isolated,including gram-negative bacteria accounting for 59.46% and gram-positive bacteria accounting for 40.54%.The drug resistance rate of gramnegative bacteria to rifampicin,imipenem,meropenem,were 0,and that to other antibacterial agents higher than42.86%;while the drug resistance rate of gram-positive bacteria to teicoplanin and vancomycin were 0,and that to other antibacterial agents were more than 50.00%.The total post-treatment effectiveness rate was 91.67%.CONCLUSION Maternal episiotomy infection pathogenic bacteria was gram-negative bacteria mainly,and sensitive antibiotic therapy for prognosis provides a better treatment.

关 键 词：会阴侧切分娩 病原菌 耐药性 

分 类 号：R619.3[医药卫生—外科学]