7种药材中重金属及有害元素的化学形态分析  

Speciation analysis for heavy metals and deleterious in seven kinds of herbs

作　　者：杨荣[1] 杨红[1] 师姣 刘峰 王娟 杨广德[1] 

机构地区：[1]西安交通大学药学院,陕西西安710061 [2]陕西步长制药有限公司,陕西咸阳721000

出　　处：《中成药》2015年第2期350-354,共5页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金项目(81373368);"十二五""重大新药创制"科技重大专项(20118x09201-2010-26;2011x09401-308-2)

摘　　要：目的了解桂枝、党参、三七、丹参、鸡血藤、牛膝、桑枝7种中药材中的重金属及有害元素存在的化学形态及分布。方法采用土壤和沉积物中常用的重金属形态分析,Tessier连续提取法制备样品,采用原子吸收分光光度法测定铜、汞、镉,铅和砷。结果 7种中药材中铜以可交换态、有机结合态和残渣态为主;砷、汞主要以不易被人体吸收铁锰氧化态、有机结合态和残渣态存在;镉、铅主要以可吸收的可交换态和碳酸盐结合态存在。结论研究结果表明,Tessier连续提取法用于中药材中有害元素的形态分析,能够提供较全面的元素信息。AIM To study the chemical speciation characteristic of heavy metals and deleterious elements in Cinnamomum cassia Presl,Codonopsis pilosula Nannf,Panax notoginseng F.H.Chen,Salvia miltiorrhiza Bge,Spatholobus suberectus Dunn,Achyranthes bidentata Bl,and Ramulus Mori.METHODS Chemical speciation analysis of heavy metals was carried out by Tessier＇s sequence extraction-routine method of determination in soil and sediment analyses.The levels of Cu,Pb,Cd,Hg and As were measured by atomic absorption spectrometry.RESULTS In the seven kinds of herbs,Cu was mainly present in exchangeable,organic and residual form.As and Hg were present in Fe-Mn oxidation,organic matter and residual state which were difficult to be absorbed by the human body.Cd and Pb mainly existed in exchangeable and carbonate states which were easy to be utilized by organism.CONCLUSION The results show that the Tessier＇s sequential extraction procedure provides more information about deleterious elements on the base of speciation analysis for heavy metals and deleterious in herbs.

关 键 词：中药材 重金属及有害元素 化学形态 TESSIER连续提取法 

分 类 号：R284.1[医药卫生—中药学]