冻干血小板的制备及其应用的研究进展  

Review of development in preparation and application of lyophilized platelets

作　　者：单桂秋[1] 耿文艳[2] 马静[1] 

机构地区：[1]广州军区广州总医院输血科,广东广州510010 [2]广州医科大学附属第三医院输血科

出　　处：《中国输血杂志》2015年第1期1-4,共4页Chinese Journal of Blood Transfusion

基　　金：国家科技重大专项课题(2011ZXJ09104-07C)

摘　　要：研究血小板冻干保存的重要目的是实现血小板的常温下长期保存,可用于静脉输注,并能将其制备成生理性止血药和促创面愈合的药物,用于战争、自然灾害、突发事件和特别偏远地区伤病员的救治。国内外研究结果表明:血小板冻干是一个特别有价值的重要研究领域,研究制备出合格的冻干血小板有极大的可能性,但目前仍有许多问题没有得到很好的解决,仍需要政府和同道们进行高度重视和深入研究,造福于伤病员的健康。To achieve the aim of long-term preservation of platelet at room temperature is one of the important purposes of the platelet freeze-drying research. In this way, freeze-dried platelets could be used for intravenous infusion. Furthermore, freeze-dried platelets could be developed as hemostatic or accelerating wound healing drugs for war, natural disasters, emer- gencies and special treatment of patients in remote areas. Both the domestic and foreign research show that the platelet freeze- drying is a particularly valuable and important research field. It is a real possibility to develop qualified lyophilized platelets. ttowever, at present there are still many problems to be resolved. It still needs government and fellow friends to pay more at- tention and carry out in-depth research for the benefit of patients.

关 键 词：血小板 冻干保存 海藻糖 止血 创面修复 

分 类 号：R331.13[医药卫生—人体生理学] R457.1[医药卫生—基础医学]