模拟血液高空坠落对血液质量影响的实验研究  

Experimental study on the influence of a free falling simulation at high altitudes on whole blood quality

作　　者：郑山根[1] 郑娅琼[1] 杨媛媛[1] 倪文旭[1] 丁尹娟[1] 刘康[1] 

机构地区：[1]广州军区武汉总医院输血科解放军武汉血站,湖北武汉430070

出　　处：《中国输血杂志》2015年第1期39-41,共3页Chinese Journal of Blood Transfusion

摘　　要：目的探讨血液高空坠落实验对不同保存时间全血质量的影响。方法将18袋全血均分为3组,在4℃下储存分别1、7、14 d后自地面作模拟高空坠落实验;肉眼观察坠落前后样品是否溶血,检测并比较每组全血坠落前后血浆游离血红蛋白(FHb)、电解质(K+、Na+)、p H值和ATP浓度。结果模拟高空坠落前后不同储存期的各组全血未见溶血,储存1和7 d的血液高空坠落后,各项指标与坠落前比较均无变化(P>0.05);储存14 d的血液高空坠落前后,FHb(mg/L)为97.4±6.2 vs 105.3±6.8(P<0.05),K+(mmol/L)11.28±1.15 vs 12.65±1.2(P<0.05)。结论模拟高空坠落对短期内库存全血质量未见改变。Abstract：Objective To explore the influence of free failing of whole blood at high altitudes on the quality of whole bloods with different preservation time. Methods Eighteen bags of whole blood were separated into three groups and were stored for one day, seven days and fourteen days at 4℃. After preservation, a free fall experiment was conducted on all bags. The presence of hemolysis was observed with naked eyes in samples before and after the experiment. The following pa- rameters, FHb, electrolyte （ K ＋ , Na ＋ ） , pH and ATP concentration of the whole blood, were compared before and after the experiment. Results Hemolysis of erythrocytes never occurred before and ＇after the free fall experiment. No significant sta- tistical differences （P 〉 0. 05 ） were found when contrasting the level of FHb, electrolyte （ K ＋ , Na＋ ）, pH and ATP concen- tration of the samples storing for one day and seven days. Before and after the free fall experiment, the level of FHb（rag/L） and K ＋ concentration（mmol/L） of the samples storing for 14 days ,were 97.4 ± 6.2 vs 105.3 ±6.8 （ P 〈 0.05 ） , and 11.28± 1.15 vs 12.65 ± 1.2（P 〈0. 05）, respectively. Conclusion Free falling simulation had no significant effect on the whole blood quality in the short term.

关 键 词：血液质量 高空坠落 溶血 游离血红蛋白 

分 类 号：R457.12[医药卫生—治疗学]