心理行为干预配合短期应用伐尼克兰的戒烟疗效观察  

Curative Effect Observation of Psychological and Behavioral Intervention Combining with Short-term Varenicline Therapy in Smoking Cessation Clinics

作　　者：江少坤[1] 孟婧婧 白卢皙[2] 崔洁玲[3] 杨烈[2,3] 

机构地区：[1]广州市第十二人民医院药剂科,广州510620 [2]广州市第十二人民医院预防保健科,广州510620 [3]广州市第十二人民医院/香港大学联合戒烟门诊,广州510620

出　　处：《中国药房》2015年第5期697-699,共3页China Pharmacy

摘　　要：目的:探讨心理行为干预配合短期应用伐尼克兰对戒烟门诊就诊者的疗效。方法:将77例戒烟门诊就诊的烟草依赖患者根据其意愿分为观察组(26例)和对照组(51例)。观察组行心理行为干预配合短期应用伐尼克兰治疗,对照组单用心理行为干预,比较两组患者的戒烟成功率及戒断症状发生率。结果:戒烟成功率观察组患者为61.54%(16/26),对照组患者为47.06%(24/51),组间差异无统计学意义(P>0.05);两组患者常见戒断症状的发生率差异无统计学意义(P>0.05)。结论:在心理行为干预基础上配合短期应用戒烟药物伐尼克兰对戒烟疗效无明显改善。OBJECTIVE： To investigate therapeutic efficacy of psychological and behavioral intervention combined with short-term varenicline therapy in the treatment of smoking cessation outpatients. METHODS： 77 subjects from smoking cessation clinics were divided into observation group （26 cases） and control group （51 cases）. Observation group received psychological and behavioral intervention combined with short-term varenicline therapy, and control group only received the treatment of psychological and behavioral intervention. The successful quitting rate and the incidence of withdraw symptoms were compared between 2 groups. RESULTS： The successful quitting rate of observation group was 61.54% （16/26） and that of control group was 43.14% （24/51）; there was no statistically significant difference （P〉0.05）. The incidence of common withdraw symptoms had no statistical differences between 2 groups （P〉0.05）. CONCLUSIONS： Short-term varenicline therapy combined with psychological and behavioral intervention could not improve smoking cessation obviously.

关 键 词：戒烟 疗效 伐尼克兰 心理行为干预 

分 类 号：R97[医药卫生—药品] R730[医药卫生—药学]