Cycloartenol triterpenoid saponins from Cimicifuga simplex(Ranunculaceae) and their biological effects  

作　　者：WU Lun CHEN Zhi-Li SU Yang WANG Qiu-Hong KUANG Hai-Xue 

机构地区：[1]Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine Ministry of Education

出　　处：《Chinese Journal of Natural Medicines》2015年第2期81-89,共9页中国天然药物（英文版）

基　　金：supported by the Fund of Education Department of Heilongjiang Province(No.201207)

摘　　要：The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9,19-cyclolanostane triterpenoid glycosides, which are distributed widely in Cimicifuga plants, but not in other members of the Ranunculaceae family, and are considered to be characteristics of the Cimicifuga genus. This type of triterpenoid glycoside possesses several important biological activities. More than 120 cycloartane triterpene glycosides have been isolated from Cimicifuga simplex Wormsk. The aim of this review article is to summarize all the major findings based on the available scientific literatures on C. simplex, with a focus on the identified 9,19-cyclolanostane triterpenoid glycosides. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9,19- cyclolanostane triterpenoid glycosides, which are distributed widely in Cimicifuga plants, but not in other members of the Ranunculaceae family, and are considered to be characteristics of the Cimicifuga genus. This type of triterpenoid glycoside possesses several important biological activities. More than 120 cycloartane triterpene glycosides have been isolated from Cimicfuga simplex Wormsk. The aim of this review article is to summarize all the major findings based on the available scientific literatures on C. simplex, with a focus on the identified 9,19-cyclolanostane triterpenoid glycosides. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.

关 键 词：Cimicifuga simplex RANUNCULACEAE Cycloartenol triterpenoid saponins Biological effects 

分 类 号：R284[医药卫生—中药学] R965[医药卫生—中医学]