早产儿代谢性骨病  

Metabolic bone disease of prematurity

作　　者：张乐嘉[1] 丁国芳[1] 

机构地区：[1]中国医学科学院北京协和医院儿科,北京100730

出　　处：《中国实用儿科杂志》2015年第2期100-104,共5页Chinese Journal of Practical Pediatrics

摘　　要：随着早产儿,尤其是极低或超低出生体重儿生存率的快速提高,早产儿代谢性骨病(也称早产儿骨质疏松)越来越引起人们的关注。其常见的病因多为钙、磷及维生素D供给不足所致,但同时也受到其他多种因素的影响。随着早产儿营养支持的迅速发展,母乳强化剂和早产儿配方奶粉已在临床中开始推广使用,代谢性骨病的发病率呈下降趋势,但其仍然是早产儿致病的重要原因之一。如何才能最好地防治此病,目前尚无明确定论。本文主要就有关早产儿代谢性骨病的病因和发病机制、临床表现、筛查、诊断方法、预防及治疗措施进行讨论。With rapid increase of survival rate of extremely low birth weight infants, metabolic bone disease of prematurity gets more and more concern. The most common reason for this disease is lack of calcium, phosphorus and vitamin D. With development of nutrition support of premature, breast milk fortifier and premature infant formula milk powder is promoted and brought into clinical use. Morbidity of metabolic bone disease decreased, but it is still the most important reason for the morbidity of premature. It is not clear what is the best way of treatment and prevention of this disease. This paper focused on the publications in recent years to explore the etiology, mechanism, clinical manifestation, screening, diagnosis, prevention and treatment measures.

关 键 词：早产儿 代谢性骨病 

分 类 号：R72[医药卫生—儿科]