慢性肾脏病及血钠紊乱与脑梗死患者预后分析  

Prognosis analysis of cerebral infraction patients with chronic kidney disease and serum sodium disorders

作　　者：邓鹏飞[1] 李递通[1] 陈玉[1] 

机构地区：[1]广西壮族自治区玉林市第二人民医院神经内科,537000

出　　处：《中国现代药物应用》2015年第5期1-3,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨首次发病的脑梗死合并慢性肾脏病及血钠紊乱患者的急性期及亚急性期预后关系,为临床防治提供依据。方法 100例既往有慢性肾脏病病史的首次发病急性脑梗死患者,收集患者入院血钠水平、肌酐、血脂等资料进行预后关系分析,计算肾小球滤过率(e GFR),比较患者入院时美国国立卫生研究院卒中量表评分(NIHSS)、发病后1个月改良的Rankin量表(MRS)评分及死亡率。结果 e GFR≤60 ml/(min·1.73 m2)患者具有更高的入院24 h内NIHSS评分及1个月后MRS评分;低钠血症患者的急性期及亚急性期预后均较差,发病1个月后的死亡率也较高,差异均具有统计学意义。结论合并肾功能损害与低钠血症的首次发病急性脑梗死患者短期预后较差。Objective To investigate the relationship of acute stage and subacute stage prognosis of ce- rebral infraction patients complicated with chronic kidney disease and serum sodium disorders, in order to provide reference for clinical prevention and treatment. Methods There were 100 patients with cerebral infraction for the first time with medical history of chronic kidney disease. Their data of serum sodium levels, creatinine, and blood lipid were collected for prognosis analysis. Estimated glomerular filtration rate （eGFR）, national institutes of health stroke scale （NIHSS） score in hospital, modified Rankin scale （MRS） score after 1 month of morbidity, and death rate were calculated. Results Patients with eGFR ≤ 60 ml/（min · 1.73 m2） had higher scores in 24 h NIHSS and MRS after I month. Patients with hyponatremia had bad acute stage and subacute stage prognosis, and their death rate after 1 month of morbidity was also high. The differences all had statistical significance （P〈0.05）. Conclusion The cerebral infarction patients with renal impairment and hyponatremia had poor short-term prognosis.

关 键 词：慢性肾脏病 血钠紊乱 脑梗死 预后 

分 类 号：R692[医药卫生—泌尿科学] R743.3[医药卫生—外科学]