222例临床全血细胞减少患者的回顾性分析  

Retrospective analysis on 222 patients with pancytopenia

作　　者：蔡颖[1] 曹永跃[1] 马亮[1] 沈军[1] 龙红[1] 曹永彤[1] 

机构地区：[1]中日友好医院检验科,北京100029

出　　处：《国际检验医学杂志》2015年第3期319-321,共3页International Journal of Laboratory Medicine

基　　金：国家科技支撑计划项目(2012BAH24F05)

摘　　要：目的探讨外周血白细胞、血红蛋白及血小板三系同时减少患者的外周血和骨髓细胞形态学特点,并分析其常见疾病类型。方法对222例2005年6月至2011年2月于该院就诊的全血细胞减少患者的骨髓涂片及外周血涂片进行瑞氏染色,结合骨髓组织化学染色及患者其他相关临床资料进行疾病类型分析。结果222例全血细胞减少患者中,造血系统疾病占84.65%(188/222),非造血系统疾病占15.35%(34/222),两者比较差异有统计学意义(P<0.05)。150例进行外周血涂片的患者中58%的患者外周血涂片结果具有诊断价值。结论引起全血细胞减少的疾病中,常见的为造血系统疾病,但也不能忽视非造血系统疾病。外周血涂片对这类疾病的诊断具有较高价值。Objective To investigate the patients′cell morphology characteristics in peripheral blood and bone marrow with the reduce of leukocyte,hemoglobin and platelet in peripheral blood,and analyze the common cause.Methods From June 2005 to February 2011,222 patients with pancytopenia treated in the hospital were enrolled in the study,whose peripheral blood and bone marrow smears were stained by Wright,combined with histochemical staining and the clinical data of patients,the disease types were analyzed.Results In the 222 patients with pancytopenia,patients with hematopoietic system disease accounted for 84.65%（188/222）,non-hematopoietic system disease accounted for 15.35%（34/222）,the difference was statistically significant（P〈0.05）.In150 patients whose peripheral blood smears were obseved,58% patients obtained positive results.Conclusion The diseases of hematopoietic system are the common cause of pancytopenia,but can not ignore the non-hematopoietic system diseases.Peripheral blood smear has a high value in the diagnosis of these diseases.

关 键 词：全血细胞减少 外周血细胞 骨髓细胞 形态学 

分 类 号：R55[医药卫生—血液循环系统疾病]