广州市社区居民慢性鼻窦炎家庭聚集性分析  

Family aggregation of chronic nasosinusitis among community residents in Guangzhou city

作　　者：张辛群 马金香[1] 史剑波[2] 付清玲[2] 

机构地区：[1]广州医科大学公共卫生学院统计学教研室,广东广州511436 [2]中山大学第一附属医院耳鼻喉科医院

出　　处：《中国公共卫生》2015年第2期168-171,共4页Chinese Journal of Public Health

基　　金：卫生行业基金专项课题(201202005)

摘　　要：目的 了解广东省广州市社区居民慢性鼻窦炎的家庭聚集性规律,为进一步探讨疾病的遗传因素或环境因素提供参考依据。方法 采用多阶段分层随机抽样在广州市4个街道8个社区抽取的517户共1521名社区居民进行问卷调查;采用β-二项分布拟合优度的χ^2检验和G统计量检验对慢性鼻窦炎家庭聚集性进行定性分析,家庭聚集性的大小估计采用组内相关系数表示。结果 广州市社区居民慢性鼻窦炎患病率为8.42%,男性和女性居民慢性鼻窦炎患病率分别为9.10%和7.75%,≤18、19~35、36~59和≥60岁居民鼻窦炎患病率分别为6.79%、10.13%、7.28%和9.27%,不同性别、年龄居民慢性鼻窦炎患病率差异均无统计学意义（P〉0.05）;慢性鼻窦炎在家庭内分布符合β-二项分布（χ^2=3.717,P=0.054）,总聚集率为22.22%;慢性鼻窦炎在不同家庭内发病概率不等（T=5.222,P〈0.001）;组内相关系数为0.094（Z=5.769,P〈0.001）;不同慢性鼻窦炎患病情况家庭比较,不同家庭居住情况、养宠物情况、家里是否铺大片地毯、住处使用的燃料类型和每月吃鱼/海鲜、水果、豆制品的频率差异均有统计学意义（P〈0.05）。结论 广州市社区居民慢性鼻窦炎存在家庭聚集性,其聚集程度较弱,但其家庭聚集性与家庭环境因素和饮食习惯有关。Objective To study family clustering of chronic nasosinusitis among community residents in Guangzhou city,Guangdong province,for researches of genetic and environmental factors of the disease. Methods A total of 1 521 residents from 517 households in 8 communities in Guangzhou city were randomly selected with multi-stage stratified ran- dom sampling for a questionnaire survey. Chi-square goodness of fit test for beta binomial distribution and G statistic were use to test family aggregation of chronic nasosinusitis qualitatively and the degree of the family aggregation was evaluated with intra-class correlation coefficient. Results The prevalence of chronic nasosinusitis in the participants was 8.42% ; no significant between-gender and between-age groups differences in the prevalence were observed, with a higher prevalence in the males than in females（9.10% vs. 7.75% ; x^2 =0. 736,P =0. 3910） and the prevalences of 6. 79%, 10. 13% ,7.28% ,and 9.27% among the participants aged ≤ 18, 19 - 35,36 - 59, and /〉60 years （x^2 =3.391, P =0. 335）. The prevalence of chronic nasosinusitis within the family showed a binomial distribution （ x^2 = 3.717, P =0. 054） ,with a total aggregation rates of 22. 22%. The probability of chronic nasosinusitis in different families was not the same（ T = 5. 222, P 〈 0. 001 ）, with an intra-class kappa correlation coefficient of 0. 094 （ Z = 5.769, P 〈 0. 001 ）. There were significant differences in chronic nasosinusitis prevalence among the families with different status of living conditions, keeping pets, using large carpet at home, type of fuel used, and dietary behaviors such as monthly consuming of fish/seafood, fruits and soy products （ all P 〈 0. 05 ）. Conclusion The family aggregation of chronic nasosinnusitis exists among community residents in Guangzhou city but the degree of the aggregation is weak and the aggregation is related to family environmental factors and dietary habits of the residents.

关 键 词：慢性鼻窦炎 家庭聚集性 社区居民 

分 类 号：R765.41[医药卫生—耳鼻咽喉科]