混合型小细胞肺癌的临床特点及诊断治疗  

Clinicopathologieal characteristics, diagnosis and treatment of combined Small cell lung cancer

作　　者：门玉[1] 惠周光[1] 

机构地区：[1]北京协和医学院中国医学科学院肿瘤医院放疗科,100021

出　　处：《国际肿瘤学杂志》2015年第2期147-149,共3页Journal of International Oncology

摘　　要：混合型小细胞肺癌是小细胞肺癌的特殊病理亚型，其发病率和诊断率均较低，但近年来有显著增加趋势。其临床特点与单纯型小细胞肺癌相似，但病变相对局限。治疗以综合治疗为主，但化疗有效率相对较低。其预后与小细胞肺癌相仿，预后因素主要有Karnofsky功能状态评分、临床分期、混合成分、肿瘤位置和大小、手术切缘等。放疗能改善局部晚期、淋巴结阳性或术后淋巴结转移较多患者的生存。Combined small cell lung cancer （C-SCLC） is a special subtype of small cell lung cancer （ SCLC）, which has a low incidence and diagnostic rate. However, the incidence and diagnostic rate appear an increasing tendency recently. The clinical features of C-SCLC are similar to the pure SCLC, while it has a rela- tively limited stage. The main treatment pattern of C-SCLC is multimodality therapy, though the response to chemotherapy in C-SCLC is relatively poor. Survival between patients with C-SCLC versus SCLC is similar. KPS, stage, composite components, tumor location and diameter, surgery margin are prognostic factors. Radiotherapy can benefit for the patients with ⅡA/ⅢB disease, positive lymph nodes, or with more metastatic lymph nodes after surgery.

关 键 词：诊断 治疗 预后 肺肿瘤 

分 类 号：R734.2[医药卫生—肿瘤]