钯催化2-羟基苯基二茂铁乙烯的合成  

Palladium-Catalyzed Synthesis of 2-Hydroxyphenyl Vinylferrocene

作　　者：刘世娟[1] 马文兵[1] 郑志花[1] 马忠平[1] 曹端林[1] 

机构地区：[1]中北大学化工与环境学院,太原030051

出　　处：《有机化学》2015年第1期228-231,共4页Chinese Journal of Organic Chemistry

摘　　要：以Pd为催化剂,实现二茂铁乙烯与邻碘(溴)苯酚化合物的交叉偶联,考察了钯催化剂种类、碱的种类、溶剂等因素对反应的影响.结果表明,在PdCl2(dppf)为催化剂,用量为5 mol%,Cs2CO3为碱,CH3CN为溶剂的条件下,可高效率高产率地得到一系列邻羟基二茂铁茋类化合物.A Pd-catalyzed method was developed for Heck-type cross-coupling reaction of a wide range of o-iodo（bromo）- phenols with vinylferrocene. The influences of different palladium catalyst, bases, solvents and other conditions were investi- gated. In the presence of PdC12（dppf）, Cs2CO3 and CH3CN, the cross-coupling products can be obtained in moderate to good yields. This catalyst system exhibits good activity in the synthesis of o-hydroxyphenyl vinylferrocene compounds.

关 键 词：HECK偶联反应 二茂铁乙烯 邻碘(溴)苯酚 钯催化 

分 类 号：O627.81[理学—有机化学]