胸腺法新对于多脏器功能障碍综合征预后的影响  

Effect of Thymalfasin for Multiple Organ Dysfunction Syndrome Prognosis

作　　者：师东武[1] 朱丽丽[1] 李喜梅[1] 宋璐[1] 

机构地区：[1]山西省人民医院,山西太原030012

出　　处：《山西职工医学院学报》2014年第6期6-8,共3页Journal of Shanxi Medical College for Continuing Education

摘　　要：目的:研究胸腺法新治疗多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)的预后的影响。方法:应用前瞻性研究方法,选择MODS病例72例,随机分为治疗组和对照组,对照组给予抗感染、纠正缺氧、改善血流动力学、代谢支持等综合治疗措施,治疗组在对照组治疗的基础上加用胸腺法新,比较两组患者治疗30 d后病死率及APACHE(Ⅱ)评分。结果:治疗组病死率17.5%低于对照组40.6%,差别有统计学意义(P<0.05);治疗组APACHE(Ⅱ)评分下降百分比为29.6±17.3,对照组为21.1±10.8,治疗组高于对照组,差别有统计学意义(P<0.05)。结论:胸腺法新可有效改善多脏器功能障碍综合症患者的预后。Objective：To study the effect of thymalfasin for multiple organ dysfunction syndrome MODS prognosis.Methods：72 patients with MODS were divided into the treatment and the control group by means of prospective study.The comprehensive treatment measures（anti infection,correcting hypoxia,hemodynamics,metabolic support） were taken to the control group;to the treatment group thymalfasin was extra applied.The death rate and APACHE（Ⅱ）scores were compared after 30-day treatment in two groups.Results：The death rate in the treatment group（17.5%）was lower than that of the control group（40.6%）.There were statistically significant differences（P〈0.05）.The percent of APACHE（Ⅱ） scores（29.6 ± 17.3） was higher than that of the control group（21.1 ± 10.8;P〈0.05） Conclusion：Thymalfasin can improve multiple organ dysfunction syndrome MODS prognosis.

关 键 词：胸腺法新 多脏器功能障碍综合症 前瞻性研究 

分 类 号：R5[医药卫生—内科学]