Preparation of Electrospun CdSe-Quantum-Dots-Doped Porous Films  

作　　者：GAO Bing SHEN Chao YUAN Shuang-long ZHANG Jian-guang YANG Yun-xia MO Xiu-mei LI Hai-yan CHEN Guo-rong 

机构地区：[1]Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East ChinaUniversity of Science and Technology, Shanghai 20023 7, China [2]College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, China [3]Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiaotong University, Shanghai 200030, China

出　　处：《Journal of Donghua University(English Edition)》2014年第5期609-616,共8页东华大学学报（英文版）

基　　金：Shanghai Leading Academic Discipline Project,China，Shanghai Key Laboratory Project,China，Doctoral Fund of Ministry of Education of China，National Natural Science Foundation of China

摘　　要：Electrospun porous films doped with the green-synthesized CdSe quantum dots were synthesized. Glycerol was chosen to prepare the quantum dots （ QDs）, with the highest quantum yield of 78.28%. Polycaprolactone （PCL） was electrospun with CdSe QDs to avoid the QDs＇ toxicity and improve the QDs＇ cytocompatibility. The electrospun QDs-doped films preserve the original QDs＇ fluorescence. Pores can be detected from the SEM of the films, predicting the possibility of loading drugs in the cancer therapy. The cell proliferation assay shows excellent cytocompatibility of the eletrospun CdSe-QDs-doped films. The present eletrospun CdSe- QDs-doped porous films are cytocompatibale, highly-fluorescent and ootential to load drugs in cancer therapy.Electrospun porous films doped with the green-synthesized CdS e quantum dots were synthesized.Glycerol was chosen to prepare the quantum dots( QDs),with the highest quantum yield of 78.28%.Polycaprolactone( PCL) was electrospun with CdS e QDs to avoid the QDs' toxicity and improve the QDs' cytocompatibility.The electrospun QDs-doped films preserve the original QDs' fluorescence.Pores can be detected from the SEM of the films,predicting the possibility of loading drugs in the cancer therapy.The cell proliferation assay shows excellent cytocompatibility of the eletrospun CdS e-QDs-doped films.The present eletrospun CdS eQDs-doped porous films are cytocompatibale,highly-fluorescent and potential to load drugs in cancer therapy.

关 键 词：CdSe-quantum dots (QDs ) ELECTROSPUN films POLYCAPROLACTONE (PCL) photoluminescence (PL) CYTOCOMPATIBILITY cell proliferation assay 

分 类 号：TB321[一般工业技术—材料科学与工程]