Effect of PLA Knitted Structure on the Mechanical Properties of Composite Vascular Scaffold  

作　　者：LI Chao-jing LI Xuan WANG Fu-jun GE Peng MAO Ying WANG Lu MARTIN W. King 

机构地区：[1]Key Laboratory of Textile Science and Technology, Ministry of Education, Donghua University, Shanghai 201620, China [2]College of Textiles, North Carolina State University, Raleigh 27695, USA

出　　处：《Journal of Donghua University(English Edition)》2014年第5期659-663,共5页东华大学学报（英文版）

基　　金：the Fundamental Research Funds for the Central Universities,China，National Natural Science Foundation of China，"111 Project" Biomedical Textile Materials Science and Technology,China，the Donghua University Innovation Fund of Graduate Project,China

摘　　要：A new entire biodegradable scaffold has been developed which does not require precellularization before transplantation.This new kind of vascular scaffold prototype made from porous poly-ε-caprolactone( PCL) membrane to provide three-dimensional environment for cell growth, and embedded with weft-knitted polylactic acid( PLA) fabric to support mechanics.The aim of this paper is to study the variation tendency of mechanical properties with the fabric spacing changing.The basic geometrical parameters were measured to characterize properties of the samples.The tensile and compressive elastic recovery of the samples were tested by the universal mechanical tester and radial compression apparatus,respectively.Both tensile and compressive properties enhanced when reducing the fabric spacing of the composite vascular scaffold.A new entire biodegradable scaffold has been developed which does not require precelluiarization before transplantation. This new kind of vascular scaffold prototype made from porous poly- e-caprolactone （PCL） membrane to provide three-dimensional environment for cell growth, and embedded with weft-knitted polylactic acid （PLA） fabric to support mechanics. The aim of this paper is to study the variation tendency of mechanical properties with the fabric spacing changing. The basic geometrical parameters were measured to characterize properties of the samples. The tensile and compressive elastic recovery of the samples were tested by the universal mechanical tester and radial compression apparatus, respectively. Both tensile and compressive properties enhanced when reducing the fabric spacing of the composite vascular scaffold.

关 键 词：vascular scaffold polylactic acid(PLA) poly-εcaprolactone(PCL) knitted fabric composite structure mechanical properties 

分 类 号：TS1[轻工技术与工程—纺织科学与工程]