中性粒细胞碱性磷酸酶阳性积分在革兰阳性球菌感染检测中的应用价值  

Evaluation of neutrophil alkaline phosphatase-positive integration in the detection of G^+ bacteria infection

作　　者：秦卫华[1] 李金秀[1] 李亚霖[1] 荣风燕 康寿磊[1] 

机构地区：[1]聊城市第二人民医院重症医学科,聊城市252600

出　　处：《中华实验和临床感染病杂志（电子版）》2014年第6期44-46,共3页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

摘　　要：目的探讨中性粒细胞碱性磷酸酶(NAP)在革兰阳性(G+)球菌中的诊断价值。方法应用快速偶氮偶联法对本科室收治的感染者141例及非感染者425例进行NAP阳性率和阳性积分检测,对比分析革兰阳性菌感染者、革兰阴性菌感染者以及非感染者的NAP阳性率和阳性积分的差异。结果革兰阳性菌感染者的NAP阳性积分为(127.4±55.7),显著高于非感染者的(89.3±46.3)和G-菌感染者的(87.3±41.7),差异具有统计学意义(P<0.05);感染和非感染组阳性积分分别为(103.2±55.7)和(87.3±41.7),两组间差异无统计学意义(P>0.05),G-菌感染组和非感染组阳性积分差异无统计学意义(P>0.05)。结论 NAP阳性积分可以作为判断革兰阳性菌感染的参考依据。Objective To explore the clinical value of analyzing neutrophil alkaline phosphatase（NAP） activity on G^＋ bacteria infection detection. Methods There were 141 cases with infection in ICU and 425 cases with no infection, patients＇ NAP positive rate and positive score were measured by AS-Bl technique. The two index of different patients were recorded and compared, respectively. Results The NAP positive score in G^＋ infection patients was（127.4 ± 55.7）, which significantly higher than that and in patients with no infection（89.3 ± 46.3） and patients with G^- infection（87.3 ± 41.7）（P〈0.05）. But there was no significant difference between patients with G^- infection and patients with no infection（P〉0.05）. And the NAP positive score in patients with infection was（103.2 ± 55.7）, there was no significant difference compared with patients with no infection（87.3 ± 41.7）（P〉0.05）. Conclusion NAP positive score could be used as a indication for G^＋ bacteria infection identification.

关 键 词：感染 中性粒细胞碱性磷酸酶 革兰阳性菌 

分 类 号：R557.3[医药卫生—血液循环系统疾病]