睡眠医学及血压变异性对合理应用降压药的临床重要性  

Sleep Medicine and Blood Pressure Variation : Significance to Clinical Application of Anti-hypertensive medicines

作　　者：马彦[1,2] 孙书臣[3] 

机构地区：[1]中国中医科学院眼科医院睡眠中心,北京100040 [2]哈佛大学医学院BIDMC医学中心多学科交叉医学部,波士顿02215 [3]中国中医科学院广安门医院耳鼻喉科,北京100053

出　　处：《世界睡眠医学杂志》2014年第4期235-238,共4页World Journal of Sleep Medicine

摘　　要：动态血压监测与偶测血压相比,能更全面更准确地反映血压的整体水平,并且能够更好地预测靶器官的损害。血压与人体的生物节律密切相关,其昼夜波动通常分为杓型、深杓型、非杓型、反杓型这四种类型的节律。血压变异性的研究与睡眠医学密不可分。针对血压的节律性变异,临床上指导患者适时适量地服用降压药是非常必要的。这既是时辰药理学关注的内容,也是睡眠医学在多学科交叉的临床实践意义之一。Compared with office blood pressure measurements,ambulatory blood pressure monitor has the advantage of revealing the general blood pressure level and better indicating target organ damage.Blood pressure is closely related to biological circadian rhythm,and commonly classified as dipping,extreme dipping,non -dipping,and reverse dipping types.The study of BP variation is inseparable to sleep medicine and BP variation should be involved in appropriate medication strategies,which is a key part to chronopharmacology,and a significant application of interdisciplinary medicine.

关 键 词：睡眠 生物节律 血压变异性 高血压 降压药 合理用药 

分 类 号：R544.1[医药卫生—心血管疾病]