连续性肾替代联合血液灌流治疗重症感染AKI的临床疗效观察  

Clinical observation of continuous renal replacement therapy combined with hem perfusion in treatment of severe infection caused by AKI

作　　者：曾蜀春[1,2] 简讯[1,2] 胡诗德[1,2] 肖胜[1,2] 

机构地区：[1]四川绵阳四○四医院 [2]川北医学院附属第二医院肾脏病科,四川绵阳621000

出　　处：《西部医学》2015年第2期203-205,共3页Medical Journal of West China

基　　金：四川省科技厅支撑计划项目(2007FGY012)

摘　　要：目的探讨连续性肾替代治疗联合血液灌流对重症感染所致急性肾损伤（AKI）患者的临床疗效。方法在2009年2月～2013年8月来我院进行治疗重症感染引起AKI的患者中抽取98例,将其随机分为对照组45例和治疗组53例,对照组患者给予间歇性血液透析联合血液灌流,治疗组患者给予连续性肾替代治疗联合血液灌流治疗。结果治疗组的死亡率显著低于对照组,且治疗组患者的住院时间和肾功能的恢复时间均小于对照组,两组间差异有统计学意义（P〈0.05）。结论连续性肾替代治疗联合血液灌流治疗能有效清除血液内的有害物质,起到保护肾脏,促进肾功恢复的作用,临床疗效优于间歇性血液透析联合血液灌流,利于患者机体的恢复,值得推广使用。Objective Continuous renal replacement therapy combined with hem perfusion in the treatment of severe infections caused by AKI were observed and discussed.Methods 98 patients with severe infection caused by the extraction of AKI were divided into the control group（n=45）and treatment group（n=53）.The control group were treated with intermittent hemodialysis combined with hem perfusion,patients in the treatment group were given continuous renal replacement therapy combined with hem perfusion.Results The treatment group was significantly lower than that of the control group,and the treatment group hospitalization time and renal function recovery time was less than that of the control group,the difference between the two groups was statistically significant（P〈0.05）.Conclusion Continuous renal replacement therapy combined with hem perfusion therapy can effectively remove harmful substances in the blood,to protect the kidney,promote the recovery of renal function,clinical curative effect is better than that of intermittent hemodialysis combined with hem perfusion,beneficial to patients with the recovery of the body,is worthy to be popularized to use.

关 键 词：AKI 连续性肾替代 血液灌流 

分 类 号：R692.5[医药卫生—泌尿科学]