127例中药注射剂不良反应分析及原因探讨  

Analysis and disscussion of the adverse drug reactions of 127 cases induced by traditional Chinese medicine injections

作　　者：沈斌[1] 周月红[1] 

机构地区：[1]嘉兴学院附属第一医院药剂科,浙江嘉兴314000

出　　处：《中华中医药杂志》2015年第2期428-431,共4页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:了解中药注射剂的不良反应发生情况,为临床用药提供参考。方法:对127例中药注射剂不良反应报告进行回顾性分析。结果:60岁以上患者49例,占38.58%。滴注30min内发生不良反应占总例数的40.16%。参麦注射液、注射用血栓通引起的药品不良反应占首位,其次为生脉注射液、刺五加注射液等。临床表现以皮肤及附件损害为主,占32.98%。结论:中药注射剂不良反应的发生与患者、药物以及临床使用不当等因素有关。应重视并加强中药注射剂的不良反应监测,促进合理用药,保证用药安全。Objective： Discussion of the adverse drug reactions（ADRs） induced by traditional Chinese medicine injections（TCMIs）, to provide a reference for clinical medication. Methods： 127 cases of ADRs induced by TCMIs were retrospectively analyzed in this article. Results： There were 49 patients with ADRs over the age of 60, accounting for 38.58%. The ADRs were found within 30 minutes accounting for 40.16%. The most of ADRs occurred in Shenmai Injection and Xueshuantong Injection, as followed Shengmai Injection and Ciwujia Injection. The ADRs focused on the damage of skin and appendage accounting for 32.98% of the total ADRs. Conclusion： The ADRs induced by TCMIs may be related to the individual constitution, drug itself and clinical misuse. It should pay more attention to monitoring the ADRs induced by TCMIs, and promoting the rational drug use to keep the medication safety.

关 键 词：中药注射剂 不良反应 分析 

分 类 号：R288[医药卫生—中药学]