5岁以下儿童呼吸双相肺密度的CT测量  

Measurement of inspiratory and expiratory lung density： a quantitative CT study in children under 5 years old

作　　者：闫洧淳[1] 袁新宇[1] 王占勇[1] 孙晶然 郭宏伟[1] 

机构地区：[1]首都儿科研究所附属儿童医院放射科,北京100020

出　　处：《中华放射学杂志》2015年第1期61-64,共4页Chinese Journal of Radiology

摘　　要：目的采用CT测量5岁以下儿童呼气末、吸气末肺组织的平均密度值。方法选取2010年1月至2012年3月在我院因外伤等疾病进行胸部CT扫描的正常肺患儿60例。通过随机数字表法分为吸气末扫描组与呼气末扫描组进行通气控制CT扫描，每组30例。获取胸部吸气末、呼气末CT图像。胸部CT图像中选取主动脉弓上2em、隆突下1cm、膈上2cm3个层面肺组织的腹侧、背侧、外侧、内侧、中心测量肺CT值。计算左肺、右肺以及全肺的平均密度值。对单侧肺吸气末、呼气末各测量区域肺密度值的变化采用单因素方差分析，各测量区域间肺密度值变化两两比较采用LSD法。结果吸气末左肺、右肺及全肺对应的肺密度值均为（-766±56）HU，呼气末相应的值分别为（-625±86）、（-647±85）、（-636±86）HU。吸气末，左肺腹侧、背侧、外侧、内侧、中心肺密度值分别为（-798±63）、（-733±68）、（-767±64）、（-754±65）、（-775±63）HU，右肺分别为（-796±70）、（-736±65）、（-769±64）、（-754±62）、（-776±59）HU；呼气末，左肺上述5个部位肺密度值分别为（-692±91）、（-555±116）、（-639±91）、（-598±103）、（-640±98）HU，右肺分别为（-712±90）、（-575±121）、（-657±90）、（-619±95）、（-670±87）HU，双肺5个测量部位在吸气末和呼气末肺密度值差异均有统计学意义（F值分别为12．55、11．29、23．31、25．47，P值均〈0．01）。5个测量部位中，背侧肺密度平均值最高，腹侧最低，其余从高到低分别为内侧、外侧、中心。结论本研究测量得到5岁以下儿童呼气末、吸气末肺组织的密度值，可为临床工作提供参考。Objective To measure the average value of CT lung density at the phase of end inspiration and end expiration in children under 5 years. Methods Sixty patients with normal lungs who underwent chest CT for reasons caused by trauma etc. in our institute from January 2010 to March 2012 were enrolled to the study. All of the patients were divided into end inspiration group and end expiration group through random number table. CT images of the phase of end inspiration and end expiration were taken. Three levels of CT images were chosen to measure the lung density, which were 2 cm above the arch, 1 cm below the carina and 2 cm above diaphragm. Lung density was measured at anterior, posterior, lateral, medial and central of the images at each level in each lung. The average lung density of each and entire lung were respectively calculated. The influence of phase, level, location was quantified using analysis of variance methods and LSD method. Results The average lung density at end inspiration was （ - 766 ±56）HU for the left, right and both lung. At end expiration, the average lung density of the left, right and both lungs was （- 625 ±86）, （- 647 ±85） and （- 636 ＋86） HU respectively. The average densities at anterior, posterior, lateral, medial and central of the left lung at end inspiration were （ - 798±63）, （- 733±68）, （- 767±64）, （- 754±65）, （- 775 ±63）HU respectively. The average densities at anterior, posterior, lateral, medial and central of the right lung were （- 796 ± 70）, （- 736 ± 65）, （- 769 ± 64）, （- 754 ± 62）, （- 776 ± 59） HU respectively. At end expiration phase, the average densities at anterior, posterior, lateral, medial and central of the left lung were （ - 692±91）, （ - 555±116）, （ - 639±91）, （ - 598±103）, （ - 640±98） HU respectively. The average densities at anterior, posterior, lateral, medial and central of the right lung were （- 712 ± 90）, （- 575±121）, （- 657±90）, （ - 619±95）, （- 670

关 键 词：儿童 体层摄影术 X线计算机 通气控制 肺密度 

分 类 号：R816.8[医药卫生—放射医学]